Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
about
Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAsBeta-globin LCR and intron elements cooperate and direct spatial reorganization for gene therapyAnimal models of β-hemoglobinopathies: utility and limitationsHeme positively regulates the expression of beta-globin at the locus control region via the transcriptional factor Bach1 in erythroid cellsGlobin gene transfer for the treatment of severe hemoglobinopathies: a paradigm for stem cell-based gene therapy.Microinjection of cre recombinase RNA induces site-specific recombination of a transgene in mouse oocytes.Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code.Globin gene transfer as a potential treatment for the beta-thalassaemias and sickle cell disease.Retrovirus silencer blocking by the cHS4 insulator is CTCF independent.Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human beta-globin in engrafted mice.Slow and Steady Wins The Race? Progress in the Development of Vectors for Gene Therapy of β-Thalassemia and Sickle Cell Disease.Amelioration of retroviral vector silencing in locus control region beta-globin-transgenic mice and transduced F9 embryonic cells.5'HS1 and the distal beta-globin promoter functionally interact in single copy beta-globin transgenic mice.
P2860
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P2860
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@ast
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@en
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@nl
type
label
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@ast
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@en
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@nl
prefLabel
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@ast
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@en
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
@nl
P2093
P2860
P356
P1476
Evaluation of beta-globin gene therapy constructs in single copy transgenic mice
@en
P2093
P2860
P304
P356
10.1093/NAR/25.6.1296
P407
P577
1997-03-01T00:00:00Z