Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.

Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.

Item
http://www.wikidata.org/entity/Q34889496
Novel Tat-encoding bicistronic human immunodeficiency virus type 1-based gene transfer vectors for high-level transgene expression.The beta-globin locus control region versus gene therapy vectors: a struggle for expression.Silencing of gene expression: implications for design of retrovirus vectors.Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code.Retrovirus silencer blocking by the cHS4 insulator is CTCF independent.Synergism between hypersensitive sites confers long-range gene activation by the beta-globin locus control region.Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase.Repression of retrovirus-mediated transgene expression by interferons: implications for gene therapyIncreased probability of expression from modified retroviral vectors in embryonal stem cells and embryonal carcinoma cells.Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation.Amelioration of retroviral vector silencing in locus control region beta-globin-transgenic mice and transduced F9 embryonic cells.Locus control region of the human CD2 gene in a lentivirus vector confers position-independent transgene expression.
P2860

Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.

Item
http://www.wikidata.org/entity/Q34889496
description
1994 nî lūn-bûn
@nan
1994 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@ast
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@en
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@nl
type
label
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@ast
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@en
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@nl
prefLabel
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@ast
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@en
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932