Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability.
about
CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil.[18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity.ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways.Reprofiling of full-length phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides toward antiproliferative agents: Synthesis, antiproliferative activity, and molecular docking study.Potential Deoxycytidine Kinase Inhibitory Activity of Amaryllidaceae Alkaloids: An Approach
P2860
Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structure-guided development o ...... improved metabolic stability.
@ast
Structure-guided development o ...... improved metabolic stability.
@en
Structure-guided development o ...... improved metabolic stability.
@nl
type
label
Structure-guided development o ...... improved metabolic stability.
@ast
Structure-guided development o ...... improved metabolic stability.
@en
Structure-guided development o ...... improved metabolic stability.
@nl
prefLabel
Structure-guided development o ...... improved metabolic stability.
@ast
Structure-guided development o ...... improved metabolic stability.
@en
Structure-guided development o ...... improved metabolic stability.
@nl
P2093
P2860
P356
P1476
Structure-guided development o ...... d improved metabolic stability
@en
P2093
Amanda L Armijo
Anastassia N Alexandrova
Arnon Lavie
Bernard D Santarsiero
Hien-Anh Nguyen
Johannes Czernin
Julian Nomme
Michael E Jung
Raymond M Gipson
P2860
P304
P356
10.1021/JM501124J
P407
P50
P577
2014-11-07T00:00:00Z