Interactions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase.
about
Chk1 suppressed cell deathHow do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA.Requirement of SLD5 for early embryogenesisNetwork architecture of signaling from uncoupled helicase-polymerase to cell cycle checkpoints and trans-lesion DNA synthesis.Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosisEnhanced H2AX phosphorylation, DNA replication fork arrest, and cell death in the absence of Chk1.Cdc45-induced loading of human RPA onto single-stranded DNA.Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage.Cell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy.Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2Snm1B interacts with PSF2.Human Cdc45 is a proliferation-associated antigen.Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase.Modification of histones by sugar β-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulatedHuman DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatinExtensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cellsCdc45 is limiting for replication initiation in humansSegregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cellsSignificant role of Psf3 expression in non-small-cell lung cancer.Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.The human GINS complex associates with Cdc45 and MCM and is essential for DNA replicationDNA replication and the GINS complex: localization on extended chromatin fibers.DNA binding properties of human Cdc45 suggest a function as molecular wedge for DNA unwinding.Multiple Sites of Type II Site Ligand (Luteolin and BMHPC) Regulation of Gene Expression in PC-3 Cells.Structural and functional insights into the DNA replication factor Cdc45 reveal an evolutionary relationship to the DHH family of phosphoesterases.MCM2-7 form double hexamers at licensed origins in Xenopus egg extract.Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells.
P2860
Q21203552-35CF50D6-836A-465B-BB7E-2D39482F8892Q24634200-B8FCCB47-16F4-4FE9-9967-AC7AD68A2333Q27938332-43FFD908-F62F-4E24-956B-6026373C45B1Q28513525-3E9CB993-9E99-4EBB-B60B-27EAFA5631F9Q33474752-D1DAD000-784A-4091-AD8D-67DF0F9CD922Q33492639-5B68621D-FF06-4C1E-B37D-030A2E89C47EQ33522347-B090BE66-6D9E-4100-9D48-85301BA93AE8Q33557735-E27DE1EA-734C-45B7-B57E-5D9AD5971D82Q33672284-93E7EB8D-EA99-4D93-8C76-3837899332E7Q34247352-8D44C44B-8176-4E6A-8C24-344FC06EC1FBQ34311881-7199DA6A-8789-43D1-A11B-CEE770CE0942Q34493793-AE726F2B-9FF2-46A3-9BE5-04D22EB97BACQ34645501-292D3E65-F3B1-49BD-9E12-0A466AAB55E6Q35312465-E0E10781-BF66-4DE9-B7F3-76D7C30B6537Q35423830-430EF7F0-3F6D-43DF-AB82-50EE1A1C0579Q35629660-13F01158-4561-4E92-B8A3-D19915244D3DQ35745476-3009D593-ED8B-4A20-8FFF-DD9E26A8E8AAQ35937274-39654DA2-24F1-4057-92A1-775B315090DAQ36286104-1AC30267-56CF-4121-9B60-9516764A59DDQ36467453-E8781A92-4F2D-4673-9F1C-B21BA6CC6986Q36549348-10EFED2D-7D2C-42A4-B6B1-17864E92089FQ37169802-1ABE7676-C34A-4152-A55B-C7BCE803AA80Q37202985-390ED751-8852-4A70-A249-31E820A7A1CAQ37606945-876523CD-F250-42F1-A14D-645D79D58EEAQ39548017-31183C3A-FFED-4AA2-B794-0C1FA396D029Q41230657-B0D3A906-F962-47AA-9D38-D15BCB95720DQ42174550-83DF8F8E-AA78-47D3-BB45-1AE3EC554881Q42726606-83D967F8-6D9C-41BC-8832-0003CE1FF603
P2860
Interactions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@ast
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@en
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@nl
type
label
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@ast
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@en
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@nl
prefLabel
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@ast
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@en
Interactions of human Cdc45 wi ...... ta and epsilon during S phase.
@nl
P2093
P2860
P1433
P1476
Interactions of human Cdc45 wi ...... lta and epsilon during S phase
@en
P2093
Christina Bauerschmidt
Elisabeth Kremmer
Frank Grosse
Sibyll Pollok
P2860
P304
P356
10.1111/J.1365-2443.2007.01090.X
P577
2007-06-01T00:00:00Z