about
Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi networkCell-surface processing of pro-ADAMTS9 by furinVersican degradation and vascular diseaseAggrecanases and cartilage matrix degradationProteoglycan aggrecan conducting T cell activation and apoptosis in a murine model of rheumatoid arthritisJAWS coordinates chondrogenesis and synovial joint positioningInhibition of furin/proprotein convertase-catalyzed surface and intracellular processing by small molecules.Role of ADAM and ADAMTS metalloproteinases in airway diseases.Mechanical load inhibits IL-1 induced matrix degradation in articular cartilageImmunological activity of chondroitin sulfate.Accumulation and loss of extracellular matrix during shear stress-mediated intimal growth and regression in baboon vascular grafts.Lack of tissue inhibitor of metalloproteinases-3 results in an enhanced inflammatory response in antigen-induced arthritis.Mechanical Loading of Articular Cartilage Reduces IL-1-Induced Enzyme ExpressionIdentification of potent and compartment-selective small molecule furin inhibitors using cell-based assays.Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification.Proteinases in the joint: clinical relevance of proteinases in joint destructionInhibition of histone deacetylases antagonized FGF2 and IL-1beta effects on MMP expression in human articular chondrocytes.Effect of Angelica sinensis Polysaccharides on Osteoarthritis In Vivo and In Vitro: A Possible Mechanism to Promote Proteoglycans SynthesisTransamidation by transglutaminase 2 transforms S100A11 calgranulin into a procatabolic cytokine for chondrocytes.Cells of the synovium in rheumatoid arthritis. Chondrocytes.Lectican proteoglycans, their cleaving metalloproteinases, and plasticity in the central nervous system extracellular microenvironment.Cartilage homeostasis in health and rheumatic diseases.Developments in the scientific understanding of osteoarthritis.Biochemistry and physiological functions of ADAMTS7 metalloprotease.Altered endochondral bone development in matrix metalloproteinase 13-deficient mice.Post-translational modification of thrombospondin type-1 repeats in ADAMTS-like 1/punctin-1 by C-mannosylation of tryptophan.BEHAB/brevican requires ADAMTS-mediated proteolytic cleavage to promote glioma invasion.The osteoarthritic niche and modulation of skeletal stem cell function for regenerative medicine.Potential directions for drug development for osteoarthritis.Current serological possibilities for the diagnosis of arthritis with special focus on proteins and proteoglycans from the extracellular matrix.Inhibition of hyaluronan export reduces collagen degradation in interleukin-1 treated cartilage.Matrilin-2 is proteolytically cleaved by ADAMTS-4 and ADAMTS-5.Lentiviral shRNA knock-down of ADAMTS-5 and -9 restores matrix deposition in 3D chondrocyte culture.Expression and activity of collagenases in the digital laminae of horses with carbohydrate overload-induced acute laminitis.Protective role of systemic furin in immune response-induced arthritis.TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors.Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.Selective inhibition of ADAMTS-1, -4 and -5 by catechin gallate esters.Comparison of gene expression profiles between dental pulp and periodontal ligament tissues in humansThe chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Aggrecanase-mediated cartilage degradation.
@ast
Aggrecanase-mediated cartilage degradation.
@en
Aggrecanase-mediated cartilage degradation.
@nl
type
label
Aggrecanase-mediated cartilage degradation.
@ast
Aggrecanase-mediated cartilage degradation.
@en
Aggrecanase-mediated cartilage degradation.
@nl
prefLabel
Aggrecanase-mediated cartilage degradation.
@ast
Aggrecanase-mediated cartilage degradation.
@en
Aggrecanase-mediated cartilage degradation.
@nl
P1476
Aggrecanase-mediated cartilage degradation.
@en
P2093
Elizabeth C Arner
P304
P356
10.1016/S1471-4892(02)00148-0
P577
2002-06-01T00:00:00Z