Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia. - Wikidata - awgldk - TriplyDB

Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.

Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.

http://www.wikidata.org/entity/Q34648608

about

Protease inhibition as new therapeutic strategy for GI diseases Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin Determinants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with Mesotrypsin Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors Serine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behavior Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates New quantitative trait loci for carotid atherosclerosis identified in an intercross derived from apolipoprotein E-deficient mouse strains.Evolution of primary hemostasis in early vertebrates The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin.Small molecule inhibitors of mesotrypsin from a structure-based docking screen.Kallikrein-related peptidase 4: a new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites.Proteinase-activated receptor-2 up-regulation by Fcgamma-receptor activation in human neutrophils Differential proteomic analysis of the pancreas of diabetic db/db mice reveals the proteins involved in the development of complications of diabetes mellitus.Serine proteases and protease-activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants.Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2)Proteinase-activated receptor-1 mediates dorsal root ganglion neuronal degeneration in HIV/AIDS.Modulation of protease-activated receptor expression by Porphyromonas gingivalis in human gingival epithelial cells.New insights into protease-activated receptor 4 signaling pathways in the pathogenesis of inflammation and neuropathic pain: a literature review Cockroach allergen serine proteinases: Isolation, sequencing and signalling via proteinase-activated receptor-2.PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer Protease-activated receptor (PAR)1, PAR2 and PAR4 expressions in esophageal squamous cell carcinoma.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.Serine proteases mediate inflammatory pain in acute pancreatitis.Biochemical and structural insights into mesotrypsin: an unusual human trypsin.Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice.Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2.Biased signaling of protease-activated receptors.Neutrophil elastase induces inflammation and pain in mouse knee joints via activation of proteinase-activated receptor-2.Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.Chemical and molecular factors in irritable bowel syndrome: current knowledge, challenges, and unanswered questions.Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1).Epithelial expression and function of trypsin-3 in irritable bowel syndrome.Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression.Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain.Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones.Dabigatran potentiates gemcitabine-induced growth inhibition of pancreatic cancer in mice.

P2860

Q26747722-AA782F64-1C89-4EFA-9A11-7F2513F52B86 Q27649308-472061E5-5C38-46E0-88AB-A6FE953E1E1F Q27664637-C594E895-6137-406E-8722-D458ED6C3A38 Q27679201-E98FBDCD-7F68-4356-A87E-F15876255DA8 Q28741929-AC3FB4A4-16C1-4181-9774-DDC8F604F77E Q30376720-683E00F8-9A6D-44F4-8836-E5329AAD88F4 Q30413841-AE0AE7DC-1EF6-4F4F-A327-AA15794CC32E Q33520927-58073A22-7902-411E-A7A7-1714BF20AD2F Q33581987-7454A757-2366-4BE1-B3D6-0A3138981F98 Q33626452-A3526352-5F90-4313-8E2E-8BAABF59F077 Q33703798-83B8B1CF-461E-443F-AF97-3AF84E0D4603 Q33846514-4B06DE29-E213-41D1-8915-697EFA4A56BE Q33895918-AB4E1D12-41AC-41BF-B031-95CE6F9F2863 Q33907542-05D49815-518D-45EE-94CF-9CF424A2CA01 Q34025076-5D7B5F49-3870-42F4-B0F1-F9CB1ACB342A Q34087958-E656DE7C-2544-490D-BD77-B0F699C12E88 Q34178822-D27A53E3-5422-4EB8-A5C8-3553B73E2ECF Q35107372-C83BE930-C313-4E6B-B6E0-7A1230AB4C68 Q35540074-19E1913A-484D-4F31-9B36-12EA1D805FDA Q35811480-DD40C0B3-22AE-4F31-82BF-D5E27111A539 Q36125100-4FD8D1D1-64DE-4000-BD62-A081AF1A5021 Q36314097-A1060926-4F01-4C74-ABFF-768F3F6D4355 Q36493144-8825EDD6-057E-4616-B6EF-BB33FCBAA0FF Q36683629-7A51829C-5627-424E-ABF1-9752D2109F9D Q36923138-60BC3AC0-46DA-45CE-BB29-0EDA5C8A0341 Q37024500-8F5DD252-3C1F-4763-9896-C1576662D9A8 Q37174647-CAC5A7D3-F6A4-4B33-B17C-1291A0724010 Q37180025-312135BA-C64B-453A-A952-5964B2B66C85 Q37251378-06EB7D28-B1D0-4DD7-A55E-57710C0FC728 Q37408317-04E01D13-EF9B-4F18-89AC-98798467AFCF Q38214613-1160DF4D-7ECA-48E1-A961-86F1DBD39834 Q38263507-681270E2-CE1A-4D2B-9968-48D24A0BBE52 Q38694104-17D902A2-B223-4D19-B6CF-A797A4647CC9 Q38800981-D9C125E0-0220-44E3-B932-0F566ABC94E7 Q39093865-AD529964-DC20-4185-ABC0-1B4CD8792206 Q39302488-42B0108D-DFF3-44AA-A97F-0EE8F4F5FA20 Q40007756-4C4A5A35-4A8F-4F6B-AD5A-6D3546B60B97 Q41298460-3A52E152-4B09-42FB-ACE0-4CC34E05DA32 Q41959040-03786475-4ACE-4AC2-842B-AA298D1C0515 Q42314537-42C8F978-E948-44FF-8BB2-ADC11AA1733E

P2860

Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.

http://www.wikidata.org/entity/Q34648608

description

2007 nî lūn-bûn

@nan

2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@ast

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@en

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@nl

type

label

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@ast

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@en

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@nl

prefLabel

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@ast

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@en

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@nl

P1433

Q34648608-FA1DCAF4-2DB0-410D-93EA-E1F9232D9A16

P1476

Q34648608-A69674C7-137C-4B15-B934-26932C89AB31

P2093

Q34648608-416127EC-3A9C-47FB-9A3A-4C4EA1CE3B1A

Q34648608-430E7275-634E-44C9-9279-FAF64588C81B

Q34648608-853422C0-1751-41A1-8335-C580F18323F3

Q34648608-99E53C63-A780-46FA-825E-E19A51781F38

Q34648608-9FCC133F-4573-4D19-A990-5335E746833C

Q34648608-C02B02CF-AA3B-4D65-9585-52F321963C49

Q34648608-CB7328B0-9658-4316-9FC1-1CB138F3F705

Q34648608-D6E1E1D8-2D7C-40BC-8309-EE8BB1A4D17F

Q34648608-DB5233F6-A0EF-418C-AFF2-C2E648DA7A5D

Q34648608-F10E6724-5537-465A-A3CE-3D0A5BBA4F14

P304

Q34648608-D700B5D6-7D44-4E9C-A553-933B8D966260

P31

Q34648608-060514BF-9EFD-449B-A1AC-0F73ECD3A568

P356

Q34648608-E645A8FF-B34E-46AC-A537-249DBD2F50BC

P407

Q34648608-A3AAD50D-874C-4CE4-849D-6883FDC7AB1D

P433

Q34648608-675686D7-E4DD-472F-AAC7-5FF447C6D386

P478

Q34648608-7A263462-89F1-4A8F-BB6C-1D5A217AE55A

P50

Q34648608-B37CE31C-6CCA-4CE9-861A-9E4CDDB7B8B1

P577

Q34648608-40B14094-61ED-47F4-92A6-823F1D5E7610

P698

Q34648608-94592D6E-0E1D-43BB-A77C-28F502E1A0D2

P356

P1433

Journal of Biological Chemistry

P1476

Trypsin IV or mesotrypsin and ...... inflammation and hyperalgesia.

@en

P2093

Anders Peterson

http://www.w3.org/2001/XMLSchema#string

Anita Skåregärde

http://www.w3.org/2001/XMLSchema#string

Graeme S Cottrell

http://www.w3.org/2001/XMLSchema#string

Johanna Mohlin

http://www.w3.org/2001/XMLSchema#string

Karin Gedda

http://www.w3.org/2001/XMLSchema#string

Kevin Chapman

http://www.w3.org/2001/XMLSchema#string

Morley D Hollenberg

http://www.w3.org/2001/XMLSchema#string

Nigel W Bunnett

http://www.w3.org/2001/XMLSchema#string

Silvia Amadesi

http://www.w3.org/2001/XMLSchema#string

Wolfgang Knecht

http://www.w3.org/2001/XMLSchema#string

P304

26089-26100

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M703840200

http://www.w3.org/2001/XMLSchema#string

P407

P433

36

http://www.w3.org/2001/XMLSchema#string

P478

282

http://www.w3.org/2001/XMLSchema#string

P50

Nathalie Vergnolle

P577

2007-07-10T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17623652

http://www.w3.org/2001/XMLSchema#string