Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1).
about
Characterization and Functions of Protease-Activated Receptor 2 in Obesity, Diabetes, and Metabolic Syndrome: A Systematic ReviewProperdin: a tightly regulated critical inflammatory modulatorProteinases, their receptors and inflammatory signalling: the Oxford South Parks Road connectionDifferential signaling by protease-activated receptors: implications for therapeutic targeting.Activated protein C: biased for translation.Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder.Diverse functional outcomes of Plasmodium falciparum ligation of EPCR: potential implications for malarial pathogenesis.PH motifs in PAR1&2 endow breast cancer growth.Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice.Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impactBiased signalling and proteinase-activated receptors (PARs): targeting inflammatory disease.Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: a role for distinct tyrosine kinase pathways.Biased signaling of protease-activated receptors.Neutrophil elastase inhibitors: a patent review and potential applications for inflammatory lung diseases (2010 - 2014).Exogenous neutrophil elastase enters bronchial epithelial cells and suppresses cigarette smoke extract-induced heme oxygenase-1 by cleaving sirtuin 1.Insights into cellular signalling by G protein coupled receptor transactivation of cell surface protein kinase receptors.Thrombin-Mediated Direct Activation of Proteinase-Activated Receptor-2: Another Target for Thrombin Signaling.Extracellular granzyme K mediates endothelial activation through the cleavage of protease-activated receptor-1.Proteinases, Their Extracellular Targets, and Inflammatory Signaling.Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in mice.Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain.Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease-activated receptor-2.Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling.Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation.Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.HNA antibody-mediated neutrophil aggregation is dependent on serine protease activity.Plasmin reduces fibronectin deposition by mesangial cells in a protease-activated receptor-1 independent manner.PAR1 Biased Signaling is Required for Activated Protein C In Vivo Benefits in Sepsis and Stroke.Platelet-neutrophil interactions as drivers of inflammatory and thrombotic disease.Proteinase 3 expression on the neutrophils of patients with paroxysmal nocturnal hemoglobinuria.Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia.A bronchoprotective role for in a murine model of lipopolysaccharide-induced airways inflammationMegakaryocytic emperipolesis and platelet function abnormalities in five patients with gray platelet syndrome
P2860
Q26752383-03A21F44-48AE-4CDA-8F30-A7CE41D52ABAQ28069187-1C6FBBE0-36AF-47CC-81FF-E1F329D5583AQ28647166-A503BA22-DD45-45B0-AFD7-6CFD8829E498Q33580620-46509BC3-1E0B-4A30-8305-827609F4F015Q35583397-EAB1DFEB-6256-4432-8AC5-E44495258A71Q36109392-B2D7B3D5-4905-4167-834D-E6AFB1A977ADQ36322439-232E2005-84B2-4835-A68B-DE9A42C9749BQ36357012-A74C63B1-6A29-4221-9816-C1E95CACB461Q37251378-FC3A70F3-8C40-45B9-9267-7ECAAE5E3F37Q37348262-B1B968B8-E954-4D2C-9FD6-48B727DAA295Q37635262-68ADF2ED-79D3-479D-9C41-521AD341FA34Q37719424-BF6EE70C-FAB1-4E6C-9AB8-1ABD0B5B796DQ38214613-63C8BC76-122A-4E58-8B46-B37A7A4936D8Q38539470-13520BF9-97E1-47FC-B142-E9417EBB5BE2Q38701061-37FAB226-7689-4B1D-8C9D-FC24E5805EADQ38760567-DCEBA4FB-810B-4CF4-9C38-64D967952FE2Q38787747-62DB4A3C-969F-4F3D-A00C-196E56A5E50BQ38789342-51289C5A-5944-4124-942D-507A93F32B26Q38966192-23096235-D69C-4277-BD59-ED75CAE361B5Q39028464-722F976F-7132-406B-837E-4768CC1D9A9EQ41298460-C97377C3-AD48-4738-BDA4-FA4C63F3BE79Q41341638-5D87C25F-A603-4686-9797-7A8833670249Q41635414-EF17F901-F073-4FB6-8016-F18EA3E6BC95Q42094761-5C9F1811-0A5F-494C-8A45-F3C35C239824Q42915550-81C8BF5F-0BD9-437D-AB74-6DE59FC678C1Q46713620-47E00550-719C-411B-A464-94FEFAEED6A9Q47142090-CE557CED-8D13-4779-8DAB-A3C850EA774CQ47855675-5F2C0A7A-14AB-40C2-9776-3E02A8944E75Q49605362-E066433C-7E8D-4E1B-BC9C-5E79AC8A7063Q50171786-D0A641E0-BB97-4585-8185-D1804CA0CD29Q55382746-7395AEB6-694F-43D3-BFF9-0CA125A16090Q57298374-F81C4C39-478C-4655-9576-511285A52D0CQ57589280-2188DA94-88A7-427A-B1EE-956B21DFBF66
P2860
Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1).
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Neutrophil elastase and protei ...... e-activated receptor-1 (PAR1).
@en
Neutrophil elastase and protei ...... roteinase-activated receptor-1
@nl
type
label
Neutrophil elastase and protei ...... e-activated receptor-1 (PAR1).
@en
Neutrophil elastase and protei ...... roteinase-activated receptor-1
@nl
prefLabel
Neutrophil elastase and protei ...... e-activated receptor-1 (PAR1).
@en
Neutrophil elastase and protei ...... roteinase-activated receptor-1
@nl
P2093
P2860
P356
P1476
Neutrophil elastase and protei ...... e-activated receptor-1 (PAR1).
@en
P2093
Bernard Renaux
Koichiro Mihara
Mahmoud Saifeddine
Morley D Hollenberg
P2860
P304
32979-32990
P356
10.1074/JBC.M113.483123
P407
P577
2013-09-19T00:00:00Z