Genome-wide determinants of proviral targeting, clonal abundance and expression in natural HTLV-1 infection
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Transcriptional and Epigenetic Regulatory Mechanisms Affecting HTLV-1 ProvirusHow does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selectionRNA stability regulates human T cell leukemia virus type 1 gene expression in chronically-infected CD4 T cells.Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis.The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma.HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP.Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression.Massive depletion of bovine leukemia virus proviral clones located in genomic transcriptionally active sites during primary infection.Clonality of HTLV-2 in natural infection.Human T-cell leukemia virus type-I Tax induces the expression of CD83 on T cells.CADM1/TSLC1 Identifies HTLV-1-Infected Cells and Determines Their Susceptibility to CTL-Mediated Lysis.T Cell Receptor Vβ Staining Identifies the Malignant Clone in Adult T cell Leukemia and Reveals Killing of Leukemia Cells by Autologous CD8+ T cells.HTLV-1 drives vigorous clonal expansion of infected CD8(+) T cells in natural infection.B'-protein phosphatase 2A is a functional binding partner of delta-retroviral integrase.CRISPR-mediated Activation of Latent HIV-1 ExpressionHTLV-1 bZIP factor protein targets the Rb/E2F-1 pathway to promote proliferation and apoptosis of primary CD4(+) T cells.Adult T-cell leukemia: molecular basis for clonal expansion and transformation of HTLV-1-infected T cells.Neuroimmunological aspects of human T cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis.HTLV-1 clonality in adult T-cell leukaemia and non-malignant HTLV-1 infection.Integration site and clonal expansion in human chronic retroviral infection and gene therapy.Inferring clonal structure in HTLV-1-infected individuals: towards bridging the gap between analysis and visualization.Human T-lymphotropic virus type 2 subtype b in a patient with chronic neurological disorder.Human T-cell leukaemia virus type 1: parasitism and pathogenesis.Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.High-Throughput Mapping and Clonal Quantification of Retroviral Integration Sites.Retroviruses integrate into a shared, non-palindromic DNA motif.Enhancement of anti-STLV-1/HTLV-1 immune responses through multimodal effects of anti-CCR4 antibodyGlucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1.Development and validation of a new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites.Involvement of double-stranded RNA-dependent protein kinase and antisense viral RNA in the constitutive NFκB activation in adult T-cell leukemia/lymphoma cells.HTLV-1-associated myelopathy/tropical spastic paraparesis.Human T-Cell Leukemia Virus Type 1 Infection and Adult T-Cell Leukemia.Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP.Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells.HTLV-1: Regulating the Balance Between Proviral Latency and Reactivation.Clonality, latency and integration of HTLV-1 in vivo.
P2860
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P2860
Genome-wide determinants of proviral targeting, clonal abundance and expression in natural HTLV-1 infection
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2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@ast
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@en
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@nl
type
label
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@ast
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@en
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@nl
prefLabel
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@ast
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@en
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@nl
P2093
P2860
P50
P1433
P1476
Genome-wide determinants of pr ...... on in natural HTLV-1 infection
@en
P2093
Daniel J Laydon
Graham P Taylor
Yuetsu Tanaka
P2860
P304
P356
10.1371/JOURNAL.PPAT.1003271
P577
2013-03-21T00:00:00Z