Essential role of stromally induced hedgehog signaling in B-cell malignancies.
about
The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinomaPharmacokinetics of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors: the role of alpha-1-acid glycoprotein bindingArsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effectorThe hedgehog pathway in triple-negative breast cancerHedgehog signaling: modulation of cancer properies and tumor mircroenvironmentHedgehog Signaling in the Maintenance of Cancer Stem CellsThe Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human CancerRoles for Hedgehog signaling in adult organ homeostasis and repairCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyAberrant activation of the hedgehog signaling pathway in malignant hematological neoplasmsHedgehog signaling pathway in ovarian cancerStromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in miceThe tumor microenvironment shapes hallmarks of mature B-cell malignancies.Molecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cellsSurvival regulation of leukemia stem cellsA possible role of mouse Fused (STK36) in Hedgehog signaling and Gli transcription factor regulationSelf-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926Critical role for mouse marginal zone B cells in PF4/heparin antibody production.Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistanceHuman bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-Hodgkin's lymphoma xenograftsIn the absence of Sonic hedgehog, p53 induces apoptosis and inhibits retinal cell proliferation, cell-cycle exit and differentiation in zebrafishThe transcription factor Gli3 promotes B cell development in fetal liver through repression of ShhTargeting Hedgehog--a cancer stem cell pathwayHedgehog signaling is dispensable for adult hematopoietic stem cell functionGANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograftHedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.A critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance.Roles of tumor suppressors in regulating tumor-associated inflammation.SMO expression in colorectal cancer: associations with clinical, pathological, and molecular featuresThe E3 ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu.Activation of the Hedgehog pathway in chronic myelogeneous leukemia patients.Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic eraCD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia.The Gli code: an information nexus regulating cell fate, stemness and cancer.Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis.Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma.The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.Targeting the Hedgehog pathway in cancerGlioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma.
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P2860
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@ast
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@en
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@nl
type
label
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@ast
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@en
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@nl
prefLabel
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@ast
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@en
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@nl
P2093
P2860
P356
P1433
P1476
Essential role of stromally induced hedgehog signaling in B-cell malignancies.
@en
P2093
Christine Dierks
Gui-Rong Guo
Joseph F Kelleher
Jovana Grbic
Katja Zirlik
Markus Warmuth
Monika Engelhardt
Nathan P Englund
Peter Schultz
Roland Mertelsmann
P2860
P2888
P304
P356
10.1038/NM1614
P407
P577
2007-07-15T00:00:00Z