Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
about
Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase(1.)The bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53.An unbiased cell morphology-based screen for new, biologically active small moleculesIn Silico Screening Reveals Structurally Diverse, Nanomolar Inhibitors of NQO2 That Are Functionally Active in Cells and Can Modulate NF- B SignalingQuinone reductase acts as a redox switch of the 20S yeast proteasome.Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development StrategyInteraction of the molecular chaperone Hsp70 with human NAD(P)H:quinone oxidoreductase 1The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathwayNAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotectorQuantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cellsBacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer.Impairment of antioxidant defenses as a contributor to arsenite-induced cell transformationNAD(P)H:quinone oxidoreductase 1 (NQO1) localizes to the mitotic spindle in human cellsCross-species genome wide expression analysis during pluripotent cell determination in mouse and rat preimplantation embryosβ-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells.ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphismNAD(P)H: quinone oxidoreductase 1 deficiency conjoint with marginal vitamin C deficiency causes cigarette smoke induced myelodysplastic syndromes.NAD(P)H quinone oxidoreductase protects TAp63gamma from proteasomal degradation and regulates TAp63gamma-dependent growth arrest.Use of NQO1 status as a selective biomarker for oesophageal squamous cell carcinomas with greater sensitivity to 17-AAGTranscriptional response of lymphoblastoid cells to ionizing radiationRelationships between metabolic and non-metabolic susceptibility factors in benzene toxicity.Dicoumarol enhances gemcitabine-induced cytotoxicity in high NQO1-expressing cholangiocarcinoma cells.PIG3 Regulates p53 Stability by Suppressing Its MDM2-Mediated UbiquitinationInhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.NQO1 stabilizes p53 through a distinct pathway.Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1.Chloroquine binding reveals flavin redox switch function of quinone reductase 2.P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1Clinical significance of NQO1 polymorphism and expression of p53, SOD2, PARP1 in limited-stage small cell lung cancerTargeting CWR22Rv1 prostate cancer cell proliferation and gene expression by combinations of the phytochemicals EGCG, genistein and quercetin.Stepping up melanocytes to the challenge of UV exposure.Amifostine alleviates radiation-induced lethal small bowel damage via promotion of 14-3-3σ-mediated nuclear p53 accumulationA systems biology analysis of metastatic melanoma using in-depth three-dimensional protein profiling.NQO1-induced activation of AMPK contributes to cancer cell death by oxygen-glucose deprivation.Prognostic significance of NQO1 expression in intrahepatic cholangiocarcinoma.The anti-tumour compound, RH1, causes mitochondria-mediated apoptosis by activating c-Jun N-terminal kinase.Ubiquitin and ubiquitin-like modifications of the p53 family.Interactive effect of smoking and NQO1 haplotypes on lung cancer risk.
P2860
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P2860
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@ast
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@en
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@nl
type
label
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@ast
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@en
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@nl
prefLabel
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@ast
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@en
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@nl
P2093
P2860
P356
P1476
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1
@en
P2093
P2860
P304
P356
10.1073/PNAS.021558898
P407
P577
2001-01-23T00:00:00Z