The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling
about
Epigenetically silenced PTPRO functions as a prognostic marker and tumor suppressor in human lung squamous cell carcinoma.High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.PTPRO represses ERBB2-driven breast oncogenesis by dephosphorylation and endosomal internalization of ERBB2Protein trafficking in colorectal carcinogenesis-targeting and bypassing resistance to currently applied treatments.Extreme Trait Whole-Genome Sequencing Identifies PTPRO as a Novel Candidate Gene in Emphysema with Severe Airflow Obstruction.Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine.EGFR expression in patients with stage III colorectal cancer after adjuvant chemotherapy and on cancer cell function.The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia.
P2860
Q33828327-5365C39E-53FB-43CA-966A-8989FA81DD30Q36113663-E49FA13A-4789-424E-B57D-26186BFBFD59Q37609203-BD08DFB6-7D55-4711-B0E7-450EE58B4E86Q38415868-76E386CE-34B9-47B1-9853-50C3323B7003Q38757264-18DB1D49-7CC4-422C-932A-973135F29A2AQ41292352-55E53782-F853-4CF8-8027-E6A7F01ACCA1Q49569642-F484C302-D16D-48A7-B7C7-7718D3D61E09Q51150640-E5692131-714F-4BBA-865E-B4A9B6BD277D
P2860
The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@ast
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@en
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@nl
type
label
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@ast
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@en
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@nl
prefLabel
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@ast
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@en
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@nl
P2093
P2860
P50
P356
P1433
P1476
The tyrosine phosphatase PTPRO ...... of SRC-mediated EGFR signaling
@en
P2093
Anna Sablina
Eva Budinska
Iria Vazquez
Layka Abbasi Asbagh
Loredana Vecchione
Mikhail Steklov
Naga-Sailaja Imjeti
Nicholas Hoe
Pascale Zimmermann
Sharat Singh
P2860
P304
10070-10083
P356
10.18632/ONCOTARGET.2458
P407
P577
2014-10-01T00:00:00Z