Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells.
about
Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways.Regulation of p27 degradation and S-phase progression by Ro52 RING finger proteinInvolvement of the DNA repair protein hHR23 in p53 degradationEpigenetics of cervical cancer. An overview and therapeutic perspectivesDifferential localization of HPV16 E6 splice products with E6-associated protein.Human Papillomavirus: Current and Future RNAi Therapeutic Strategies for Cervical CancerThe Role of Infectious Agents in the Etiology of Ocular Adnexal NeoplasiaFunctional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical SitesIntrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cellsC1 Domain-targeted isophthalate derivatives induce cell elongation and cell cycle arrest in HeLa cellsSkp2B stimulates mammary gland development by inhibiting REA, the repressor of the estrogen receptorStructure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1.Role of the ubiquitin system and tumor viruses in AIDS-related cancer.The ubiquitin system, disease, and drug discovery.The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.Combining Oncolytic Virotherapy with p53 Tumor Suppressor Gene TherapyActivating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53Involvement of nuclear export in human papillomavirus type 18 E6-mediated ubiquitination and degradation of p53.GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers.Cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of PP2A to induce cell cycle arrest/apoptosis and inhibits tumor progression.Pitx2a binds to human papillomavirus type 18 E6 protein and inhibits E6-mediated P53 degradation in HeLa cells.PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53-MDM2 loop.The ING4 Binding with p53 and Induced p53 Acetylation were Attenuated by Human Papillomavirus 16 E6.MG132 inhibition of proteasome blocks apoptosis induced by severe DNA damage.Tumor viruses and cell signaling pathways: deubiquitination versus ubiquitinationKnock down of p53 or its ubiquitin ligase E6AP does not affect the sensitivity of human papillomavirus-positive cervical cancer cells to cisplatin.p53 polymorphism in human papillomavirus-associated Kazakh's esophageal cancer in Xinjiang, ChinaYY1 is a novel potential therapeutic target for the treatment of HPV infection-induced cervical cancer by arsenic trioxide.HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53.Human papilloma virus DNA exposure and embryo survival is stage-specific.RNA interference for the treatment of papillomavirus disease.HPV16 E6 and E7 proteins induce a chronic oxidative stress response via NOX2 that causes genomic instability and increased susceptibility to DNA damage in head and neck cancer cells.E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis.HPV16 E6 upregulates Aurora A expression.c-MYC responds to glucose deprivation in a cell-type-dependent mannerThe human papillomavirus E7 oncoprotein.Emerging biological treatments for uterine cervical carcinoma.
P2860
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P2860
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@ast
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@en
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@nl
type
label
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@ast
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@en
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@nl
prefLabel
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@ast
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@en
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@nl
P2093
P2860
P356
P1476
Complete switch from Mdm2 to h ...... p53 in cervical cancer cells.
@en
P2093
A Hengstermann
L K Linares
N J Whitaker
P2860
P304
P356
10.1073/PNAS.031470698
P407
P577
2001-01-23T00:00:00Z