The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical and pharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus.
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Landmark studies on the glucagon subfamily of GPCRs: from small molecule modulators to a crystal structureHuman GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon ProductionSmall molecule glucagon receptor antagonists: a patent review (2011 - 2014).Investigational glucagon receptor antagonists in Phase I and II clinical trials for diabetes.Effects of multiple ascending doses of the glucagon receptor antagonist PF-06291874 in patients with type 2 diabetes mellitus.
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The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical and pharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus.
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2013 nî lūn-bûn
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2013 թուականի Մարտին հրատարակուած գիտական յօդուած
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2013 թվականի մարտին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
The design and synthesis of a ...... t of type 2 diabetes mellitus.
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The design and synthesis of a ...... t of type 2 diabetes mellitus.
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The design and synthesis of a ...... t of type 2 diabetes mellitus.
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The design and synthesis of a ...... t of type 2 diabetes mellitus.
@ast
The design and synthesis of a ...... t of type 2 diabetes mellitus.
@en
The design and synthesis of a ...... t of type 2 diabetes mellitus.
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The design and synthesis of a ...... t of type 2 diabetes mellitus.
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The design and synthesis of a ...... t of type 2 diabetes mellitus.
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The design and synthesis of a ...... t of type 2 diabetes mellitus.
@nl
P2093
P1476
The design and synthesis of a ...... t of type 2 diabetes mellitus.
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P2093
Angel Guzman-Perez
Beijing Tan
Benjamin D Stevens
Brian Samas
Christian Perreault
Christopher T Salatto
Dianna Moore
Esther C Y Lee
Gary E Aspnes
Janice Brown
P304
P356
10.1016/J.BMCL.2013.03.014
P407
P577
2013-03-13T00:00:00Z