TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. - Wikidata - awgldk - TriplyDB

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

http://www.wikidata.org/entity/Q34662448

about

miRNA response to DNA damage Non-Coding RNA: Sequence-Specific Guide for Chromatin Modification and DNA Damage Signaling Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors Molecular basis of cleft palates in mice miRNA biogenesis: biological impact in the development of cancer Links between mutant p53 and genomic instability Noncoding RNAs in DNA repair and genome integrity Tumor suppressor p53 and its gain-of-function mutants in cancer The miR-200 and miR-221/222 microRNA families: opposing effects on epithelial identity MicroRNA biogenesis pathways in cancer miRNA Deregulation in Cancer Cells and the Tumor Microenvironment The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System The microRNA feedback regulation of p63 in cancer progression Control by a hair's breadth: the role of microRNAs in the skin Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion.DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition TAp63 suppress metastasis via miR-133b in colon cancer cells.Regulation of p63 protein stability via ubiquitin-proteasome pathway.DNA damage induces expression of WWP1 to target ΔNp63α to degradation TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.Hepatic p63 regulates steatosis via IKKβ/ER stress ΔNp63 isoform-mediated β-defensin family up-regulation is associated with (lymph)angiogenesis and poor prognosis in patients with squamous cell carcinoma.∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.OCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation.Prognostic significance of low DICER expression regulated by miR-130a in cervical cancer p53/p63/p73 in the epidermis in health and disease ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2.The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformation DeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance Alteration of miRNA activity via context-specific modifications of Argonaute proteins.p53 Isoforms: An Intracellular Microprocessor?MicroRNA-194 is a target of transcription factor 1 (Tcf1, HNF1α) in adult liver and controls expression of frizzled-6.microRNA expression and biogenesis in cellular response to ionizing radiation p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling.Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors.Altered expression of the miRNA processing endoribonuclease Dicer has prognostic significance in human cancers.

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P2860

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

http://www.wikidata.org/entity/Q34662448

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@ast

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@en

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@nl

type

label

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@ast

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@en

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@nl

prefLabel

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@ast

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@en

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

@nl

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TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

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P2093

Adel El-Naggar

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Chad J Creighton

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Deepavali Chakravarti

http://www.w3.org/2001/XMLSchema#string

Elsa R Flores

http://www.w3.org/2001/XMLSchema#string

Lingzhi Liu

http://www.w3.org/2001/XMLSchema#string

Marco L Leung

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Milind B Suraokar

http://www.w3.org/2001/XMLSchema#string

Min Soon Cho

http://www.w3.org/2001/XMLSchema#string

Xiaohua Su

http://www.w3.org/2001/XMLSchema#string

Young Jin Gi

http://www.w3.org/2001/XMLSchema#string

P2860

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

TAp63 prevents premature aging by promoting adult stem cell maintenance

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

MicroRNA expression profiles classify human cancers

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

A microRNA component of the p53 tumour suppressor network

Tumor spectrum analysis in p53-mutant mice

Impaired microRNA processing enhances cellular transformation and tumorigenesis

On the shoulders of giants: p63, p73 and the rise of p53.

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.

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986-990

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scholarly article

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10.1038/NATURE09459

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7318

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467

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Ignacio I Wistuba

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2010-10-01T00:00:00Z

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20962848

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