A small molecule inhibitor of fungal histone acetyltransferase Rtt109. - Wikidata - awgldk - TriplyDB

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

http://www.wikidata.org/entity/Q34669591

about

Histone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferases A cell-free fluorometric high-throughput screen for inhibitors of Rtt109-catalyzed histone acetylation Pneumocystis jirovecii Rtt109, a novel drug target for Pneumocystis pneumonia in immunosuppressed humans PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS.Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.The WOR1 5' untranslated region regulates white-opaque switching in Candida albicans by reducing translational efficiency Histone acetyltransferase inhibitors: where art thou?Environmental change drives accelerated adaptation through stimulated copy number variation.Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors.Structural characterization of the Asf1-Rtt109 interaction and its role in histone acetylation.

P2860

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P2860

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

http://www.wikidata.org/entity/Q34669591

description

2013 nî lūn-bûn

@nan

2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@ast

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@en

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@nl

type

label

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@ast

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@en

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@nl

prefLabel

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@ast

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@en

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@nl

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J.BMCL.2013.03.112

P1433

Bioorganic & Medicinal Chemistry Letters

P1476

A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

@en

P2093

James Spoonamore

http://www.w3.org/2001/XMLSchema#string

Jessica Lopes da Rosa

http://www.w3.org/2001/XMLSchema#string

Paul D Kaufman

http://www.w3.org/2001/XMLSchema#string

Vineeta Bajaj

http://www.w3.org/2001/XMLSchema#string

P2860

Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA

Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

Structural insights into histone H3 lysine 56 acetylation by Rtt109

Molecular basis for the autoregulation of the protein acetyl transferase Rtt109

Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75

Rtt109 is required for proper H3K56 acetylation: a chromatin mark associated with the elongating RNA polymerase II.

Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109.

Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly

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2853-2859

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10.1016/J.BMCL.2013.03.112

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10

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