New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
about
Topoisomerase I function during Escherichia coli response to antibiotics and stress enhances cell killing from stabilization of its cleavage complex.Targeting bacterial topoisomerase I to meet the challenge of finding new antibiotics.Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents.A simplified protocol for high-yield expression and purification of bacterial topoisomerase I.3,4-dimethoxyphenyl bis-benzimidazole, a novel DNA topoisomerase inhibitor that preferentially targets Escherichia coli topoisomerase IMolecular analysis and anticancer properties of two identified isolates, Fusarium solani and Emericella nidulans isolated from Wady El-Natron soil in Egypt against Caco-2 (ATCC) cell line.The fluoroquinolone levofloxacin triggers the transcriptional activation of iron transport genes that contribute to cell death in Streptococcus pneumoniae.Topoisomerases: Resistance versus Sensitivity, How Far We Can Go?An increase in negative supercoiling in bacteria reveals topology-reacting gene clusters and a homeostatic response mediated by the DNA topoisomerase I gene.The Transcriptome of Streptococcus pneumoniae Induced by Local and Global Changes in Supercoiling.Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases.Type IA DNA Topoisomerases: A Universal Core and Multiple Activities.HU of Streptococcus pneumoniae Is Essential for the Preservation of DNA Supercoiling.
P2860
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P2860
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@ast
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@en
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@nl
type
label
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@ast
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@en
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@nl
prefLabel
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@ast
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@en
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@nl
P2093
P2860
P356
P1476
New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
@en
P2093
Adela G de la Campa
Juan A Hermoso
María Amparo Blázquez
María Jesús Sanz
María José Ferrándiz
María Teresa García
Noella Silva-Martín
P2860
P304
P356
10.1074/JBC.M110.148148
P407
P577
2010-12-17T00:00:00Z