IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2 - Wikidata - awgldk - TriplyDB

IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2

IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2

http://www.wikidata.org/entity/Q34687371

about

The role of miRNAs in regulating gene expression networks Assessing specific oligonucleotides and small molecule antibiotics for the ability to inhibit the CRD-BP-CD44 RNA interaction.Inhibition of CYFIP2 promotes gastric cancer cell proliferation and chemoresistance to 5-fluorouracil through activation of the Akt signaling pathway.An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model.Molecular insights into the coding region determinant-binding protein-RNA interaction through site-directed mutagenesis in the heterogeneous nuclear ribonucleoprotein-K-homology domains.High-throughput fluorescence anisotropy screen for inhibitors of the oncogenic mRNA binding protein, IMP-1.miRNA-196b inhibits cell proliferation and induces apoptosis in HepG2 cells by targeting IGF2BP1 Circulating microRNAs as potential biomarkers for endometriosis.A Novel Role for VICKZ Proteins in Maintaining Epithelial Integrity during Embryogenesis.Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor Cells Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.Silencing of high-mobility group box 2 (HMGB2) modulates cisplatin and 5-fluorouracil sensitivity in head and neck squamous cell carcinoma.Bioinformatic analysis of microRNA networks following the activation of the constitutive androstane receptor (CAR) in mouse liver Characterizing the Coding Region Determinant-Binding Protein (CRD-BP)-Microphthalmia-associated Transcription Factor (MITF) mRNA interaction.Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon.Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts.Role of 3'-untranslated region translational control in cancer development, diagnostics and treatment.CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome.Therapeutic potential of microRNA let-7: tumor suppression or impeding normal stemness.Inhibition of GLI1 Expression by Targeting the CRD-BP-GLI1 mRNA Interaction Using a Specific Oligonucleotide.Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia.Regulation of Stem Cell Self-Renewal and Oncogenesis by RNA-Binding Proteins.miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma.IGF2BP1 controls cell death and drug resistance in rhabdomyosarcomas by regulating translation of cIAP1.Gene expression profiling of anti-CTLA4-treated metastatic melanoma in patients with treatment-induced autoimmunity.Post-transcriptional regulation of cyclins D1, D3 and G1 and proliferation of human cancer cells depend on IMP-3 nuclear localization.A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation.MicroRNA Profile to Predict Gemcitabine Resistance in Bladder Carcinoma Cell Lines.Cis-acting elements in its 3' UTR mediate post-transcriptional regulation of KRAS.Effects of IGF2BP2, KCNQ1 and GCKR polymorphisms on clinical outcome in metastatic gastric cancer treated with EOF regimen.Abrogating the interplay between IGF2BP1, 2 and 3 and IGF1R by let-7i arrests hepatocellular carcinoma growth.Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in cancer.The Molecular Basis and Therapeutic Potential of Let-7 MicroRNAs against Colorectal Cancer.

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P2860

IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2

http://www.wikidata.org/entity/Q34687371

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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name

IMP-1 displays cross-talk with ...... el proapoptotic protein CYFIP2

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IMP-1 displays cross-talk with ...... el proapoptotic protein CYFIP2

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IMP-1 displays cross-talk with ...... el proapoptotic protein CYFIP2

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IMP-1 displays cross-talk with ...... el proapoptotic protein CYFIP2

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IMP-1 displays cross-talk with ...... el proapoptotic protein CYFIP2

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0008-5472.CAN-10-3295

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Cancer Research

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Anil K Rustgi

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Antoni Castells

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Cameron N Johnstone

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Catrina E King

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Felicite K Noubissi

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Jiri Kalabis

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Mark J Bowser

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Miriam Cuatrecasas

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Perry S Mongroo

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Vladimir S Spiegelman

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P2860

A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development

Identification of c-MYC as a target of the APC pathway

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

Widespread microRNA repression by Myc contributes to tumorigenesis

Suppression of non-small cell lung tumor development by the let-7 microRNA family

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

The tumor suppressor microRNA let-7 represses the HMGA2 oncogene.

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2172-2182

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scholarly article

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10.1158/0008-5472.CAN-10-3295

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6

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71

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2011-01-20T00:00:00Z

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49771733

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21252116

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3059369

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