Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex. - Wikidata - awgldk - TriplyDB

Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex.

Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex.

http://www.wikidata.org/entity/Q34693662

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Processing of microRNA primary transcripts requires heme in mammalian cells Synchrony in schizophrenia: a window into circuit-level pathophysiology Converging levels of analysis on a genomic hotspot for psychosis: insights from 22q11.2 deletion syndrome Neuronal migration abnormalities and its possible implications for schizophrenia Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia.Involvement of microRNA in microglia-mediated immune response Dimerization and Heme Binding Are Conserved in Amphibian and Starfish Homologues of the microRNA Processing Protein DGCR8 Molecular mechanisms in 22q11 deletion syndrome.Modeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit development The Emerging Role of microRNAs in Schizophrenia and Autism Spectrum Disorders Cellular functions of the microprocessor Haploinsufficiency of the 22q11.2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium.Exome sequencing supports a de novo mutational paradigm for schizophrenia.Modeling psychiatric disorders at the cellular and network levels Deletion Extents Are Not the Cause of Clinical Variability in 22q11.2 Deletion Syndrome: Does the Interaction between DGCR8 and miRNA-CNVs Play a Major Role?MicroRNA Machinery Genes as Novel Biomarkers for Cancer Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome.NMDA mediated contextual conditioning changes miRNA expression Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia.Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome The RNA-centred view of the synapse: non-coding RNAs and synaptic plasticity Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.Expression of miRNAs and their cooperative regulation of the pathophysiology in traumatic brain injury MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review.MicroRNA Dysregulation, Gene Networks, and Risk for Schizophrenia in 22q11.2 Deletion Syndrome Insights on the functional impact of microRNAs present in autism-associated copy number variants.Evidence demonstrating role of microRNAs in the etiopathology of major depression Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder.Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice.Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing.Cause or Effect: Misregulation of microRNA Pathways in Neurodegeneration.Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants The Path to microRNA Therapeutics in Psychiatric and Neurodegenerative Disorders Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation.Excessive attractor instability accounts for semantic priming in schizophrenia.Caspases cleave and inhibit the microRNA processing protein DiGeorge Critical Region 8.DGCR8 HITS-CLIP reveals novel functions for the Microprocessor.SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.Altered short-term plasticity in the prefrontal cortex after early life seizures.

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P2860

Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex.

http://www.wikidata.org/entity/Q34693662

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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PNAS.1101219108

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Proceedings of the National Academy of Sciences of the United States of America

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Deficiency of Dgcr8, a gene di ...... city in the prefrontal cortex.

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Amy B Macdermott

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Bin Xu

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Joseph A Gogos

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Jun Mukai

http://www.w3.org/2001/XMLSchema#string

Karine Fénelon

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Liam J Drew

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Maria Karayiorgou

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Pei-Ken Hsu

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P2860

Advances in autism genetics: on the threshold of a new neurobiology

An integrative theory of prefrontal cortex function

Theta rhythms coordinate hippocampal-prefrontal interactions in a spatial memory task

Short-term synaptic plasticity

Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors

SOX5 controls the sequential generation of distinct corticofugal neuron subtypes

Postnatal neurodevelopmental disorders: meeting at the synapse?

22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia.

Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation.

Identification of the hippocampal input to medial prefrontal cortex in vitro.

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4447-4452

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10.1073/PNAS.1101219108

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11

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108

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Gerald Fischbach

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2011-02-28T00:00:00Z

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50267162

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21368174

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3060227

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