Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli - Wikidata - awgldk - TriplyDB

Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli

Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli

http://www.wikidata.org/entity/Q34697729

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Physiology of the read-write genome Bacterial Responses and Genome Instability Induced by Subinhibitory Concentrations of Antibiotics Reactive Oxygen Species Play an Important Role in the Bactericidal Activity of Quinolone Antibiotics A chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivo Critical amino acids in human DNA polymerases eta and kappa involved in erroneous incorporation of oxidized nucleotides.Antibiotics induce redox-related physiological alterations as part of their lethality.Epistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage.Translesion DNA Synthesis.Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda.Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains β-Lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity.Controlling mutation: intervening in evolution as a therapeutic strategy.Multiple strategies for translesion synthesis in bacteria The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa.Low-mutation-rate, reduced-genome Escherichia coli: an improved host for faithful maintenance of engineered genetic constructs.Transcriptional modulator NusA interacts with translesion DNA polymerases in Escherichia coli.Lytic infection of Lactococcus lactis by bacteriophages Tuc2009 and c2 triggers alternative transcriptional host responses.Oxidative DNA damage defense systems in avoidance of stationary-phase mutagenesis in Pseudomonas putida.RpoS, the stress response sigma factor, plays a dual role in the regulation of Escherichia coli's error-prone DNA polymerase IV.

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P2860

Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli

http://www.wikidata.org/entity/Q34697729

description

2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2006 թվականի հուլիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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name

Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

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Journal of Bacteriology

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Involvement of Y-family DNA po ...... ucleotides in Escherichia coli

@en

P2093

Hideyoshi Harashima

http://www.w3.org/2001/XMLSchema#string

Hiroyuki Kamiya

http://www.w3.org/2001/XMLSchema#string

Masatomi Shimizu

http://www.w3.org/2001/XMLSchema#string

Petr Gruz

http://www.w3.org/2001/XMLSchema#string

Takehiko Nohmi

http://www.w3.org/2001/XMLSchema#string

Tatsuo Nunoshiba

http://www.w3.org/2001/XMLSchema#string

P2860

The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein

Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase

All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis

MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

The Y-family of DNA polymerases

The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity

2-Hydroxy-dATP is incorporated opposite G by Escherichia coli DNA polymerase III resulting in high mutagenicity.

SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification.

Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli.

Adaptive mutation in Escherichia coli.

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4992-4995

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scholarly article

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10.1128/JB.00281-06

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13

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188

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2006-07-01T00:00:00Z

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16788208

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Escherichia coli

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1482991

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