Attenuation of AMPA receptor activity improves motor skills in a mouse model of juvenile Batten disease.
about
Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease)Abnormally increased surface expression of AMPA receptors in the cerebellum, cortex and striatum of Cln3(-/-) miceTreatment of the Ppt1(-/-) mouse model of infantile neuronal ceroid lipofuscinosis with the N-methyl-D-aspartate (NMDA) receptor antagonist memantine.Safety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders.Seizure susceptibility, phenotype, and resultant growth delay in the nclf and mnd mouse models of neuronal ceroid lipofuscinoses.Immunosuppression alters disease severity in juvenile Batten disease miceAge-dependent therapeutic effect of memantine in a mouse model of juvenile Batten diseaseAltered sensitivity of cerebellar granule cells to glutamate receptor overactivation in the Cln3(Δex7/8)-knock-in mouse model of juvenile neuronal ceroid lipofuscinosis.Temporary inhibition of AMPA receptors induces a prolonged improvement of motor performance in a mouse model of juvenile Batten diseaseImmune-mediated epilepsies.Finding the most appropriate mouse model of juvenile CLN3 (Batten) disease for therapeutic studies: the importance of genetic background and gender.Progress in the Development of Small Molecule Therapeutics for the Treatment of Neuronal Ceroid Lipofuscinoses (NCLs).Therapeutic approaches to the challenge of neuronal ceroid lipofuscinoses.Neuropeptide changes and neuroactive amino acids in CSF from humans and sheep with neuronal ceroid lipofuscinoses (NCLs, Batten disease).Juvenile neuronal ceroid lipofuscinosis (JNCL) and the eye.Efficacy of phosphodiesterase-4 inhibitors in juvenile Batten disease (CLN3).Clinical trials in rare disease: challenges and opportunities.The AMPA receptor as a therapeutic target: current perspectives and emerging possibilities.New AMPA antagonists in epilepsy.Altered glutamate receptor function in the cerebellum of the Ppt1-/- mouse, a murine model of infantile neuronal ceroid lipofuscinosisThe fission yeast model for the lysosomal storage disorder Batten disease predicts disease severity caused by mutations in CLN3.Altered sensitivity to excitotoxic cell death and glutamate receptor expression between two commonly studied mouse strains.Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons.Microglia in juvenile neuronal ceroid lipofuscinosis are primed toward a pro-inflammatory phenotype.Juvenile neuronal ceroid-lipofuscinosis: clinical and molecular investigation in a large family in Brazil.Altered Cerebellar Short-Term Plasticity but No Change in Postsynaptic AMPA-Type Glutamate Receptors in a Mouse Model of Juvenile Batten Disease.Searching for novel biomarkers using a mouse model of CLN3-Batten disease
P2860
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P2860
Attenuation of AMPA receptor activity improves motor skills in a mouse model of juvenile Batten disease.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@ast
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@en
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@nl
type
label
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@ast
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@en
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@nl
prefLabel
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@ast
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@en
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@nl
P2860
P1476
Attenuation of AMPA receptor a ...... el of juvenile Batten disease.
@en
P2093
Attila D Kovács
David A Pearce
P2860
P304
P356
10.1016/J.EXPNEUROL.2007.09.012
P407
P577
2007-10-25T00:00:00Z