Segmental genomic replacement in embryonic stem cells by double lox targeting
about
Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases.The Ashwell receptor mitigates the lethal coagulopathy of sepsisGeneration of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementationAn efficient method to successively introduce transgenes into a given genomic locus in the mouseMinimal cross-recombination between wild-type and loxP511 sites in vivo facilitates truncating both ends of large DNA inserts in pBACe3.6 and related vectors.Hematopoietic overexpression of FOG1 does not affect B-cells but reduces the number of circulating eosinophilsSPO11-independent DNA repair foci and their role in meiotic silencingMosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereociliaPost-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapmentModeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organizationCre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines.Immunologic applications of conditional gene modification technology in the mouseSite-directed integration of the cre gene mediated by Cre recombinase using a combination of mutant lox sitesThoc1/Hpr1/p84 is essential for early embryonic development in the mouse.Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy.Dual roles for hepatic lectin receptors in the clearance of chilled plateletsRedesign of the monomer-monomer interface of Cre recombinase yields an obligate heterotetrameric complex.An intrinsic mechanism of secreted protein aging and turnoverGene trap mutagenesis in mice: new perspectives and tools in cancer research.Studying human telomerase gene transcription by a chromatinized reporter generated by recombinase-mediated targeting of a bacterial artificial chromosome.Conditional gene targeting: dissecting the cellular mechanisms of retinal degenerations.Cre-loxP-Mediated Recombination: General Principles and Experimental Considerations.Recombinase mediated cassette exchange into genomic targets using an adenovirus vector.Site-specific recombination in Schizosaccharomyces pombe and systematic assembly of a 400kb transgene array in mammalian cells using the integrase of Streptomyces phage phiBT1.Negative selection with the Diphtheria toxin A fragment gene improves frequency of Cre-mediated cassette exchange in ES cells.Alteration of Cre recombinase site specificity by substrate-linked protein evolution.Gene-trap-based target site for cre-mediated transgenic insertion.Occurrence of free sialyl oligosaccharides related to N-glycans (sialyl free N-glycans) in animal sera.Cell-penetrating peptide-driven Cre recombination in porcine primary cells and generation of marker-free pigs.Characterization of Cre-mediated cassette exchange after plasmid microinjection in fertilized mouse oocytes.A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells.
P2860
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P2860
Segmental genomic replacement in embryonic stem cells by double lox targeting
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Segmental genomic replacement in embryonic stem cells by double lox targeting
@ast
Segmental genomic replacement in embryonic stem cells by double lox targeting
@en
Segmental genomic replacement in embryonic stem cells by double lox targeting
@nl
type
label
Segmental genomic replacement in embryonic stem cells by double lox targeting
@ast
Segmental genomic replacement in embryonic stem cells by double lox targeting
@en
Segmental genomic replacement in embryonic stem cells by double lox targeting
@nl
prefLabel
Segmental genomic replacement in embryonic stem cells by double lox targeting
@ast
Segmental genomic replacement in embryonic stem cells by double lox targeting
@en
Segmental genomic replacement in embryonic stem cells by double lox targeting
@nl
P2093
P356
P1476
Segmental genomic replacement in embryonic stem cells by double lox targeting
@en
P2093
P356
10.1093/NAR/27.18.E21
P407
P577
1999-09-01T00:00:00Z