Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy.
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Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epitheliumKnockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo.Noninvasive two-photon microscopy imaging of mouse retina and retinal pigment epithelium through the pupil of the eye.Multiphoton adaptation of a commercial low-cost confocal microscope for live tissue imaging.In vivo imaging of microscopic structures in the rat retinaCone survival despite rod degeneration in XOPS-mCFP transgenic zebrafishTopical mydriatics affect light-evoked retinal responses in anesthetized mice.A high content screening approach to identify molecules neuroprotective for photoreceptor cellsAdaptive optics retinal imaging in the living mouse eyeAbrupt onset of mutations in a developmentally regulated gene during terminal differentiation of post-mitotic photoreceptor neurons in mice.In vitro expanded stem cells from the developing retina fail to generate photoreceptors but differentiate into myelinating oligodendrocytes.Outer segment formation of transplanted photoreceptor precursor cellsRhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutantProbing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations.A conditional immortalized mouse muller glial cell line expressing glial and retinal stem cell genesA G protein-coupled receptor (GPCR) in red: live cell imaging of the kappa opioid receptor-tdTomato fusion protein (KOPR-tdT) in neuronal cells.G protein-coupled receptor rhodopsin.Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice.Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosaA FRAP-Based Method for Monitoring Molecular Transport in Ciliary Photoreceptor Cells In Vivo.Novel Methodology for Creating Macaque Retinas with Sortable Photoreceptors and Ganglion Cells.Neural reprogramming in retinal degeneration.Signals governing the trafficking and mistrafficking of a ciliary GPCR, rhodopsin.The severe autosomal dominant retinitis pigmentosa rhodopsin mutant Ter349Glu mislocalizes and induces rapid rod cell death.A review of in vivo animal studies in retinal prosthesis research.Phospholipids are needed for the proper formation, stability, and function of the photoactivated rhodopsin-transducin complex.Prolonged blockade of VEGF receptors does not damage retinal photoreceptors or ganglion cells.Conditional gene targeting: dissecting the cellular mechanisms of retinal degenerations.Cell replacement and visual restoration by retinal sheet transplantsThe Molecular Chaperone GRP78/BiP as a Therapeutic Target for Neurodegenerative Disorders: A Mini Review.Gene expression changes during retinal development and rod specification.Fluorescent knock-in mice to decipher the physiopathological role of G protein-coupled receptors.Aberrant protein trafficking in retinal degenerations: The initial phase of retinal remodeling.A common microRNA signature in mouse models of retinal degeneration.Phosphatidylinositol-3-phosphate is light-regulated and essential for survival in retinal rods.Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosaEpitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalizationLive-cell imaging evidence for the ciliary transport of rod photoreceptor opsin by heterotrimeric kinesin-2.Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death.Two-photon imaging of the mammalian retina with ultrafast pulsing laser
P2860
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P2860
Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy.
description
2004 nî lūn-bûn
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2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@ast
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@en
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@nl
type
label
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@ast
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@en
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@nl
prefLabel
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@ast
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@en
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@nl
P2093
P2860
P356
P1476
Knock-in human rhodopsin-GFP f ...... and targets for gene therapy.
@en
P2093
Allan Bradley
John H Wilson
Theodore G Wensel
P2860
P304
P356
10.1073/PNAS.0403149101
P407
P577
2004-06-07T00:00:00Z