Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents.
about
Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancerCrystal structure and snapshots along the reaction pathway of a family 51 -L-arabinofuranosidaseStructures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitorBiochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.Loop-tryptophan human purine nucleoside phosphorylase reveals submillisecond protein dynamics.Forodesine: review of preclinical and clinical data.Preclinical and clinical evaluation of forodesine in pediatric and adult B-cell acute lymphoblastic leukemiaComputational methods for de novo protein design and its applications to the human immunodeficiency virus 1, purine nucleoside phosphorylase, ubiquitin specific protease 7, and histone demethylases.Conformational dynamics in human purine nucleoside phosphorylase with reactants and transition-state analoguesA proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine)Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cellsRemote mutations and active site dynamics correlate with catalytic properties of purine nucleoside phosphorylase.Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma.Modulating Enzyme Catalysis through Mutations Designed to Alter Rapid Protein Dynamics.Modeling inflammatory bowel disease: the zebrafish as a way forward.Cutaneous T-cell lymphoma: Biologic targets for therapy.Targeted therapies for cutaneous T-cell lymphomas.8-Azapurines as isosteric purine fluorescent probes for nucleic acid and enzymatic research.Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H.A complex of methylthioadenosine/S-adenosylhomocysteine nucleosidase, transition state analogue, and nucleophilic water identified by mass spectrometry.Allosteric Communication Networks in Proteins Revealed through Pocket Crosstalk AnalysisTunable diastereoselection of biased rigid systems by Lewis acid induced conformational effects: a rationalization of the vinylation of cyclic nitrones en route to polyhydroxylated pyrrolidines.
P2860
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P2860
Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Development of transition stat ...... orylase as anti-T-cell agents.
@ast
Development of transition stat ...... orylase as anti-T-cell agents.
@en
Development of transition stat ...... orylase as anti-T-cell agents.
@nl
type
label
Development of transition stat ...... orylase as anti-T-cell agents.
@ast
Development of transition stat ...... orylase as anti-T-cell agents.
@en
Development of transition stat ...... orylase as anti-T-cell agents.
@nl
prefLabel
Development of transition stat ...... orylase as anti-T-cell agents.
@ast
Development of transition stat ...... orylase as anti-T-cell agents.
@en
Development of transition stat ...... orylase as anti-T-cell agents.
@nl
P1476
Development of transition stat ...... orylase as anti-T-cell agents.
@en
P2093
Vern L Schramm
P304
P356
10.1016/S0925-4439(02)00073-X
P407
P577
2002-07-01T00:00:00Z