A mode-of-action approach for the identification of genotoxic carcinogens.
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Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge aheadCorrelation of In Vivo Versus In Vitro Benchmark Doses (BMDs) Derived From Micronucleus Test Data: A Proof of Concept StudyGenotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach.Genotoxicity of flubendazole and its metabolites in vitro and the impact of a new formulation on in vivo aneugenicity.Role of Trisomy 21 Mosaicism in Sporadic and Familial Alzheimer's Disease.Empirical analysis of BMD metrics in genetic toxicology part I: in vitro analyses to provide robust potency rankings and support MOA determinations.Complementarity of phosphorylated histones H2AX and H3 quantification in different cell lines for genotoxicity screening.Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.Quantitative analysis of the relative mutagenicity of five chemical constituents of tobacco smoke in the mouse lymphoma assay.Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents.A tripartite mode of action approach for investigating the impact of aneugens on tubulin polymerization.Quantitative differentiation of whole smoke solution-induced mutagenicity in the mouse lymphoma assay.Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment.New approaches to advance the use of genetic toxicology analyses for human health risk assessment
P2860
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P2860
A mode-of-action approach for the identification of genotoxic carcinogens.
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A mode-of-action approach for the identification of genotoxic carcinogens.
@ast
A mode-of-action approach for the identification of genotoxic carcinogens.
@en
A mode-of-action approach for the identification of genotoxic carcinogens.
@nl
type
label
A mode-of-action approach for the identification of genotoxic carcinogens.
@ast
A mode-of-action approach for the identification of genotoxic carcinogens.
@en
A mode-of-action approach for the identification of genotoxic carcinogens.
@nl
prefLabel
A mode-of-action approach for the identification of genotoxic carcinogens.
@ast
A mode-of-action approach for the identification of genotoxic carcinogens.
@en
A mode-of-action approach for the identification of genotoxic carcinogens.
@nl
P2093
P2860
P1433
P1476
A mode-of-action approach for the identification of genotoxic carcinogens.
@en
P2093
George E Johnson
Jan van Benthem
Lya G Hernández
P2860
P304
P356
10.1371/JOURNAL.PONE.0064532
P407
P577
2013-05-13T00:00:00Z