6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2. - Wikidata - awgldk - TriplyDB

6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2.

6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2.

http://www.wikidata.org/entity/Q34734125

about

Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation Prediction of molecular targets of cancer preventing flavonoid compounds using computational methods Isolation, bioactivity, and production of ortho-hydroxydaidzein and ortho-hydroxygenistein The daidzein metabolite, 6,7,4'-Trihydroxyisoflavone, is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1.High-throughput RNAi screening of human kinases identifies predictors of clinical outcome in colorectal cancer patients treated with oxaliplatin.Production of Two Novel Methoxy-Isoflavones from Biotransformation of 8-Hydroxydaidzein by Recombinant Escherichia coli Expressing O-Methyltransferase SpOMT2884 from Streptomyces peucetius.Establishment of human metastatic colorectal cancer model in rabbit liver: A pilot study Signal transduction and molecular targets of selected flavonoids.Soy Saponins Meditate the Progression of Colon Cancer in Rats by Inhibiting the Activity of β -Glucuronidase and the Number of Aberrant Crypt Foci but Not Cyclooxygenase-2 Activity.Accumulation of cytoplasmic Cdk1 is associated with cancer growth and survival rate in epithelial ovarian cancer Target molecules of food phytochemicals: food science bound for the next dimension.The relationship between structure and in vitro antibacterial activity of selected isoflavones and their metabolites with special focus on antistaphylococcal effect of demethyltexasin.Estrogen receptor β potentiates the antiproliferative effect of raloxifene and affects the cell migration and invasion in HCT-116 colon cancer cells.Molecular docking analysis of known flavonoids as duel COX-2 inhibitors in the context of cancer.Inhibitory effects of resveratrol on hepatitis B virus X-protein (HBx)-induced hepatocellular carcinoma (HCC).Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.Jianpi Huayu Decoction Inhibits Proliferation in Human Colorectal Cancer Cells (SW480) by Inducing G0/G1-Phase Cell Cycle Arrest and Apoptosis.A metabolite of daidzein, 6,7,4'-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K.The ethanol extracts of sporoderm-broken spores of Ganoderma lucidum inhibit colorectal cancer in vitro and in vivo.

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P2860

6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2.

http://www.wikidata.org/entity/Q34734125

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2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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Ann M Bode

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Bo Yeon Kim

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Dong Eun Lee

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Eun Jung Lee

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Hyong Joo Lee

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Jung A Hwang

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Ki Won Lee

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Sung Keun Jung

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Tae-Gyu Lim

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Zigang Dong

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P2860

Cell cycle, CDKs and cancer: a changing paradigm

Gut bacterial metabolism of the soy isoflavone daidzein: exploring the relevance to human health

Cyclin-dependent kinase pathways as targets for cancer treatment

Soybeans, Soy Foods, Isoflavones and Risk of Colorectal Cancer: a Review of Experimental and Epidemiological Data.

Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines.

Oxidative in vitro metabolism of the soy phytoestrogens daidzein and genistein.

Chemoprevention of colorectal cancer: dietary and pharmacologic approaches.

Epigenetic events during the process of cell transformation induced by carcinogens (review).

Epidemiology and molecular genetics of colorectal cancer.

Cancer statistics, 2000.

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629-635

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scholarly article

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10.1093/CARCIN/BGR008

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4

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32

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