Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
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BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasomeIdentification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5Role of ceramide in diabetes mellitus: evidence and mechanisms.Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanismsLoss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death.Characteristics of the rat cardiac sphingolipid pool in two mitochondrial subpopulationsTargeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemiaFurther characterization of mammalian ceramide kinase: substrate delivery and (stereo)specificity, tissue distribution, and subcellular localization studies.Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia.Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death.Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.(R)-α-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria.Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis.Elevation of GM2 ganglioside during ethanol-induced apoptotic neurodegeneration in the developing mouse brain.Sphingomyelinase depresses force and calcium sensitivity of the contractile apparatus in mouse diaphragm muscle fibers.Metabolic profiles revealed synergistically antidepressant effects of lilies and Rhizoma Anemarrhenae in a rat model of depression.Mitochondrial ceramide and the induction of apoptosisDiabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy.Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism.Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy.Accumulation of ordered ceramide-cholesterol domains in farber disease fibroblasts.Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction.Novel chemotherapeutic drugs in sphingolipid cancer research.Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.Syndromes of neurodegeneration with brain iron accumulation (NBIA): an update on clinical presentations, histological and genetic underpinnings, and treatment considerations.Ceramide function in the brain: when a slight tilt is enough.Allylic structures in cancer drugs and body metabolites that control cell life and death.Sphingolipids and mitochondrial apoptosis.Regulation of ceramide channel formation and disassembly: Insights on the initiation of apoptosis.5,7,3'-Trihydroxy-3,4'-dimethoxyflavone inhibits the tubulin polymerization and activates the sphingomyelin pathway.Mulberry fruit (Moris fructus) extracts induce human glioma cell death in vitro through ROS-dependent mitochondrial pathway and inhibits glioma tumor growth in vivo.Ceramides modulate programmed cell death in plants.A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria.Overcoming resistance to gamma-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels.Membrane permeabilization induced by sphingosine: effect of negatively charged lipids.Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA).Sphingosine increases the permeability of model and cell membranesMitochondrial ceramide increases in UV-irradiated HeLa cells and is mainly derived from hydrolysis of sphingomyelin.Loss of ceramide kinase in Arabidopsis impairs defenses and promotes ceramide accumulation and mitochondrial H2O2 bursts.
P2860
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P2860
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@ast
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@en
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@nl
type
label
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@ast
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@en
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@nl
prefLabel
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@ast
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@en
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@nl
P2093
P1476
Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
@en
P2093
Helene Birbes
Lina M Obeid
Samer El Bawab
P304
P356
10.1016/S0065-2571(01)00026-7
P577
2002-01-01T00:00:00Z