Viewing the antigen-induced initiation of B-cell activation in living cells.
about
B cell activation involves nanoscale receptor reorganizations and inside-out signaling by SykThe constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.Intrinsic properties of immunoglobulin IgG1 isotype-switched B cell receptors promote microclustering and the initiation of signalingFormation of a mast cell synapse: Fc epsilon RI membrane dynamics upon binding mobile or immobilized ligands on surfaces.A balance of Bruton's tyrosine kinase and SHIP activation regulates B cell receptor cluster formation by controlling actin remodeling.Vamp-7-dependent secretion at the immune synapse regulates antigen extraction and presentation in B-lymphocytes.Small, mobile FcepsilonRI receptor aggregates are signaling competent.Antigen affinity discrimination is an intrinsic function of the B cell receptor.It's all about change: the antigen-driven initiation of B-cell receptor signalingDistribution and dynamics of rat basophilic leukemia immunoglobulin E receptors (FcepsilonRI) on planar ligand-presenting surfaces.How B cells capture, process and present antigens: a crucial role for cell polarity.Analysis of molecular diffusion by first-passage time variance identifies the size of confinement zonesMonte Carlo study of B-cell receptor clustering mediated by antigen crosslinking and directed transport.Actin reorganization is required for the formation of polarized B cell receptor signalosomes in response to both soluble and membrane-associated antigens.The adaptor protein Crk controls activation and inhibition of natural killer cells.A method for analyzing protein-protein interactions in the plasma membrane of live B cells by fluorescence resonance energy transfer imaging as acquired by total internal reflection fluorescence microscopy.Monte Carlo study of single molecule diffusion can elucidate the mechanism of B cell synapse formationFormation of BCR oligomers provides a mechanism for B cell affinity discrimination.The network of receptors characterize B cell receptor micro- and macroclustering in a Monte Carlo model.Discrimination of membrane antigen affinity by B cells requires dominance of kinetic proofreading over serial engagement.Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.Understanding B cell activation: from single molecule tracking, through Tolls, to stalking memory in malariaThe cellular context of T cell signaling.Dynamics of membrane trafficking downstream of B and T cell receptor engagement: impact on immune synapses.Actin-mediated feedback loops in B-cell receptor signaling.The actin cytoskeleton coordinates the signal transduction and antigen processing functions of the B cell antigen receptor.Invariant Chain Complexes and Clusters as Platforms for MIF Signaling.Studying MHC class II presentation of immobilized antigen by B lymphocytes.Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin.Monte Carlo investigation of diffusion of receptors and ligands that bind across opposing surfaces.Modeling of B cell Synapse Formation by Monte Carlo Simulation Shows That Directed Transport of Receptor Molecules Is a Potential Formation Mechanism.The Problem of Antigen Affinity Discrimination in B-Cell Immunology
P2860
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P2860
Viewing the antigen-induced initiation of B-cell activation in living cells.
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Viewing the antigen-induced initiation of B-cell activation in living cells.
@ast
Viewing the antigen-induced initiation of B-cell activation in living cells.
@en
Viewing the antigen-induced initiation of B-cell activation in living cells.
@nl
type
label
Viewing the antigen-induced initiation of B-cell activation in living cells.
@ast
Viewing the antigen-induced initiation of B-cell activation in living cells.
@en
Viewing the antigen-induced initiation of B-cell activation in living cells.
@nl
prefLabel
Viewing the antigen-induced initiation of B-cell activation in living cells.
@ast
Viewing the antigen-induced initiation of B-cell activation in living cells.
@en
Viewing the antigen-induced initiation of B-cell activation in living cells.
@nl
P2093
P2860
P1476
Viewing the antigen-induced initiation of B-cell activation in living cells.
@en
P2093
Hae Won Sohn
Pavel Tolar
Susan K Pierce
P2860
P356
10.1111/J.1600-065X.2008.00583.X
P577
2008-02-01T00:00:00Z