Antigen affinity discrimination is an intrinsic function of the B cell receptor. - Wikidata - awgldk - TriplyDB

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

http://www.wikidata.org/entity/Q33839911

about

Cross-presentation of IgG-containing immune complexes The growth of B cell receptor microcluster is a universal response of B cells encountering antigens with different motion features Understanding the initiation of B cell signaling through live cell imaging.FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling.A new and robust method of tethering IgG surrogate antigens on lipid bilayer membranes to facilitate the TIRFM based live cell and single molecule imaging experiments.Intrinsic properties of immunoglobulin IgG1 isotype-switched B cell receptors promote microclustering and the initiation of signaling Intrinsic differences in the initiation of B cell receptor signaling favor responses of human IgG(+) memory B cells over IgM(+) naive B cells.B cells use mechanical energy to discriminate antigen affinities.The autoinhibitory C-terminal SH2 domain of phospholipase C-γ2 stabilizes B cell receptor signalosome assembly.Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.Germinal center B cells recognize antigen through a specialized immune synapse architecture.A Rough Energy Landscape to Describe Surface-Linked Antibody and Antigen Bond Formation.No receptor stands alone: IgG B-cell receptor intrinsic and extrinsic mechanisms contribute to antibody memory IgE-binding epitopes: a reappraisal.It's all about change: the antigen-driven initiation of B-cell receptor signaling Encoding immunological memory in the initiation of B-cell receptor signaling Germinal center selection and the development of memory B and plasma cells.B-cell receptor signaling as a driver of lymphoma development and evolution.The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module.Monte Carlo study of B-cell receptor clustering mediated by antigen crosslinking and directed transport.N-wasp is essential for the negative regulation of B cell receptor signaling.Etiopathogenesis of insulin autoimmunity.The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold.Megakaryocyte progenitors are the main APCs inducing Th17 response to lupus autoantigens and foreign antigens Identification of Ezrin-Radixin-Moesin proteins as novel regulators of pathogenic B-cell receptor signaling and tumor growth in diffuse large B-cell lymphoma.The tipping points in the initiation of B cell signalling: how small changes make big differences.The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors.Acidic phospholipids govern the enhanced activation of IgG-B cell receptor Utilization of a photoactivatable antigen system to examine B-cell probing termination and the B-cell receptor sorting mechanisms during B-cell activation.Formation of BCR oligomers provides a mechanism for B cell affinity discrimination.Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases.Discrimination of membrane antigen affinity by B cells requires dominance of kinetic proofreading over serial engagement.Ezrin tunes the magnitude of humoral immunity.Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232.Regulation of B cell fate by chronic activity of the IgE B cell receptor.The nanoscale spatial organization of B-cell receptors on immunoglobulin M- and G-expressing human B-cells.Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D.The dissociation activation model of B cell antigen receptor triggering.Inside the microcluster: antigen receptor signalling viewed with molecular imaging tools.The pivotal position of the actin cytoskeleton in the initiation and regulation of B cell receptor activation.

P2860

Q26825801-2146012C-92F2-477A-A2D3-DEEC70EE50AB Q27340390-9CB0928E-B4D2-4935-9C93-D253746FC208 Q28681231-9134B6E8-0029-4704-9074-1FCB38FBF99B Q30423426-74521B33-DA1E-4F96-ACDE-A15BF65AD664 Q30454349-38561D57-7DFA-4340-84B4-419C17935514 Q30495504-B6725E4D-705F-4BD0-9D00-A494F8272D06 Q30511975-E95A98AD-67F0-43FE-A152-51B8095674C6 Q30541546-51A07BC7-5320-4BCB-B1C5-434F2782C726 Q30588609-41EF7DD0-7A4A-43F7-8E32-CF933F15829D Q30620402-40FD3F78-3DC1-49DE-A320-029B62DE92D6 Q30784700-FC648997-2755-4A14-800B-592136258296 Q30820933-0A6D0C6F-E0FF-4182-930F-39FC6FF36DBE Q33701856-EEFB8D5A-1D7D-4D78-A0DC-AD0032B3A345 Q33915536-987E3644-4367-4ABC-A9AC-F17DFD9E8EC4 Q33931940-C173FB18-22F5-4592-BB67-E00DE21D9E10 Q34147466-E9818226-63F9-4E12-88C5-5465D23F9609 Q34268133-BEA10096-04A5-47B1-8697-5C5D838DE4C6 Q34398579-AB42481B-7253-42E5-9CFF-0FB417059D88 Q34677828-05B6C20B-E623-4FD0-BDEF-7667CFE3EFDF Q34917778-798526F2-FAA0-4D3E-AE87-6507C06C97C2 Q35040533-27A824E3-8817-4667-A896-B800E4326562 Q35910119-D7DA8224-A8E3-42C7-A8B8-F757C8668F51 Q36014751-F3438BC3-860E-49F7-970E-01748C1A5443 Q36016443-487EF5AD-F40B-4F87-958B-2E968689869A Q36021623-AE25397F-7C82-4898-BE51-996383FF42CA Q36121790-3A3CA432-F7EC-4B48-8F9C-248F58C169B7 Q36145652-1A9F1BED-FFB0-48A5-8910-C956D7C7B99A Q36145918-FEB4D42C-BD5B-4134-81EF-37906482C5CF Q36563167-F999E4C7-EA5F-4063-B434-3F3E3FD7E537 Q36975865-839AC183-F23A-4968-B6A8-D534E00338E1 Q37091486-D2DACCFB-7B7C-4B57-9D11-261491F7F156 Q37130271-A185ECA9-6E6F-45E3-9599-24A95A8349FC Q37256630-2A8FB48C-02CE-44E1-BA52-37874762B956 Q37415229-EC4449E2-47F4-4418-808D-45C3D9F9D64B Q37552578-566F1E19-B160-471E-B69A-FA14137CBACA Q37639033-543F0F89-D80F-449A-9967-56499343E80C Q37644030-EF51B803-5C15-402D-B110-BA9F49A11DCF Q37797618-444401B8-547C-46A2-8D54-7F457D73A2B7 Q37875893-0419D7BB-8CA7-4D91-9BA9-BFA355E8E593 Q38124186-398CE200-2AFC-4D1C-B1E3-F568689F149F

P2860

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

http://www.wikidata.org/entity/Q33839911

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

@ast

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

@en

type

label

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

@ast

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

@en

prefLabel

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

@ast

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

@en

P1433

Q33839911-551585B4-C510-4E07-826D-052B7D734B96

P1476

Q33839911-D6B24D27-866F-4966-93F8-2549FDE37070

P2093

Q33839911-1DEFC825-BE83-43FA-8078-8E67C8233300

Q33839911-A8AC85B2-B06C-4501-B79F-27D0BA10F9AF

Q33839911-B9F66835-6AEC-4A67-84EB-57122112141E

Q33839911-E89EFCF9-3A6D-4FC8-8927-21C18451BB15

P2860

Q33839911-0071B5D2-8D55-4703-88DC-57BF626C1C3E

Q33839911-0F2B5D5C-E01A-40BC-B756-FF4320525265

Q33839911-1674EB87-8BB2-400C-993F-F0BD15E9FBB0

Q33839911-1A70C452-2593-44A5-B559-7DF694D858A3

Q33839911-1C5738B8-0E04-4928-99E0-0522C045E182

Q33839911-2193DF53-74C1-4C11-822E-B8D8AC6BF6D3

Q33839911-24FB3C25-935F-4B54-8250-BA2AADBCBDE9

Q33839911-32B3E891-A60A-492C-896A-43CE577219D5

Q33839911-353DBBF6-F52A-45B8-9680-3F4C165572C3

Q33839911-3ACE9664-CA30-490B-9E76-20D2EE34B8C3

P304

Q33839911-DDE1202E-13F1-4E60-9FFE-79ACC12E93D9

P31

Q33839911-3BCB3BEF-783A-43F7-A73A-80BE21B8DE94

P356

Q33839911-D229AF48-7512-42F7-B319-B3DEAF380BBF

P407

Q33839911-7C432205-05CD-4B34-8BE3-4A2981BC6B18

P433

Q33839911-1DD11089-1A17-46B7-814E-4D2D6CDEAFA2

P478

Q33839911-224442E1-18D6-40A5-A610-62AD2223EE0D

P50

Q33839911-43A2E66C-EA62-4C4A-B4D7-A5CFD1E41E33

P577

Q33839911-7C2BC2D0-6687-4BFC-BD1C-8EB77445348C

P5875

Q33839911-391BFAED-F688-45D5-8E38-6DB66B99AFD5

P698

Q33839911-ABE972A5-4523-4C21-ABCB-344C09BA30B7

P932

Q33839911-04353908-4451-42A4-BDCA-093CAC6D0A7D

P356

P1433

Journal of Experimental Medicine

P1476

Antigen affinity discrimination is an intrinsic function of the B cell receptor

@en

P2093

Hae Won Sohn

http://www.w3.org/2001/XMLSchema#string

Pavel Tolar

http://www.w3.org/2001/XMLSchema#string

Susan K Pierce

http://www.w3.org/2001/XMLSchema#string

Tobias Meckel

http://www.w3.org/2001/XMLSchema#string

P2860

The immunological synapse: a molecular machine controlling T cell activation

SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates

Methods of Digital Video Microscopy for Colloidal Studies

The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.

Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells.

Effects of jasplakinolide on the kinetics of actin polymerization. An explanation for certain in vivo observations.

The initiation of antigen-induced B cell antigen receptor signaling viewed in living cells by fluorescence resonance energy transfer.

The who, how and where of antigen presentation to B cells.

Fluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signaling

Viewing the antigen-induced initiation of B-cell activation in living cells.

P304

1095-1111

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20092123

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

207

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-04-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

43201472

http://www.w3.org/2001/XMLSchema#string

P698

20404102

http://www.w3.org/2001/XMLSchema#string

P932

2867278

http://www.w3.org/2001/XMLSchema#string