ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage - Wikidata - awgldk - TriplyDB

ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

http://www.wikidata.org/entity/Q34753639

about

PKCδ stabilizes TAp63 to promote cell apoptosis DNA repair and aging: the impact of the p53 family The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System Regulation of p63 protein stability via ubiquitin-proteasome pathway.ROS-PIASγ cross talk channelizes ATM signaling from resistance to apoptosis during chemosensitization of resistant tumors.Bioinformatics study of cancer-related mutations within p53 phosphorylation site motifs Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure.Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation Tumor protein p63/nuclear factor κB feedback loop in regulation of cell death.Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance.Structural prediction of the interaction of the tumor suppressor p27KIP1 with cyclin A/CDK2 identifies a novel catalytically relevant determinant Phospho-ΔNp63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance p63 the guardian of human reproduction.Phospho-ΔNp63α/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure p53-family proteins and their regulators: hubs and spokes in tumor suppression.Phospho-ΔNp63α/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas Novel mechanism links p63 and cisplatin resistance.Photodynamic treatment with hexyl-aminolevulinate mediates reversible thiol oxidation in core oxidative stress signaling proteins.PMS2 expression in epithelial ovarian cancer is posttranslationally regulated by Akt and essential for platinum-induced apoptosis.Phospho-ΔNp63α-responsive microRNAs contribute to the regulation of necroptosis in squamous cell carcinoma upon cisplatin exposure.Phospho-ΔNp63α-dependent microRNAs modulate chemoresistance of squamous cell carcinoma cells to cisplatin: at the crossroads of cell life and death.Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation.Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells.Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells.DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation.Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress.Tumor Protein p63/microRNA Network in Epithelial Cancer Cells.Human papillomavirus E7 induces p63 expression to modulate DNA damage response.JNK1 inhibits transcriptional and pro-apoptotic activity of TAp63γ.HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.

P2860

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P2860

ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

http://www.wikidata.org/entity/Q34753639

description

2008 nî lūn-bûn

@nan

2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

ATM kinase is a master switch ...... arcinoma cells upon DNA damage

@ast

ATM kinase is a master switch ...... arcinoma cells upon DNA damage

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ATM kinase is a master switch ...... arcinoma cells upon DNA damage

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type

label

ATM kinase is a master switch ...... arcinoma cells upon DNA damage

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ATM kinase is a master switch ...... arcinoma cells upon DNA damage

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ATM kinase is a master switch ...... arcinoma cells upon DNA damage

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prefLabel

ATM kinase is a master switch ...... arcinoma cells upon DNA damage

@ast

ATM kinase is a master switch ...... arcinoma cells upon DNA damage

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ATM kinase is a master switch ...... arcinoma cells upon DNA damage

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ATM kinase is a master switch ...... arcinoma cells upon DNA damage

@en

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Barry Trink

http://www.w3.org/2001/XMLSchema#string

David Sidransky

http://www.w3.org/2001/XMLSchema#string

Edward Ratovitski

http://www.w3.org/2001/XMLSchema#string

Jatin Nagpal

http://www.w3.org/2001/XMLSchema#string

Sunil Upadhyay

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Tanusree Sen

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Yiping Huang

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P2860

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

Overcoming cisplatin resistance by mTOR inhibitor in lung cancer.

Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

Probability-based protein identification by searching sequence databases using mass spectrometry data

Substrate specificities and identification of putative substrates of ATM kinase family members

Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes

DeltaNp63 plays an anti-apoptotic role in ventral bladder development

p63 is an essential proapoptotic protein during neural development

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10.4161/CC.7.18.6627

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18

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7

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23233888

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18769144

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head and neck squamous cell carcinoma

phosphorylation

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3069617

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