Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice. - Wikidata - awgldk - TriplyDB

Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice.

Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice.

http://www.wikidata.org/entity/Q34756083

about

Skeletal Muscle Pathology in X-Linked Myotubular Myopathy: Review With Cross-Species Comparisons Pharmacology of manipulating lean body mass Congenital myopathies: an update Pathophysiological concepts in the congenital myopathies: blurring the boundaries, sharpening the focus Selenoprotein N deficiency in mice is associated with abnormal lung development Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C mice Tissue triage and freezing for models of skeletal muscle disease.AAV-microdystrophin therapy improves cardiac performance in aged female mdx mice.Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype Myotubularin-deficient myoblasts display increased apoptosis, delayed proliferation, and poor cell engraftment.Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models.Enzyme replacement therapy rescues weakness and improves muscle pathology in mice with X-linked myotubular myopathy.Treatment with ActRIIB-mFc Produces Myofiber Growth and Improves Lifespan in the Acta1 H40Y Murine Model of Nemaline Myopathy.Association of the K153R polymorphism in the myostatin gene and extreme longevity.Potentially diagnostic electron paramagnetic resonance spectra elucidate the underlying mechanism of mitochondrial dysfunction in the deoxyguanosine kinase deficient rat model of a genetic mitochondrial DNA depletion syndrome Myostatin inhibitors as therapies for muscle wasting associated with cancer and other disorders Mitochondrial impairment induced by postnatal ActRIIB blockade does not alter function and energy status in exercising mouse glycolytic muscle in vivo.Myostatin inhibition using mRK35 produces skeletal muscle growth and tubular aggregate formation in wild type and TgACTA1D286G nemaline myopathy mice.Neonatal Systemic AAV-Mediated Gene Delivery of GDF11 Inhibits Skeletal Muscle Growth.Goat activin receptor type IIB knockdown by artificial microRNAs in vitro.Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal Muscle.Centronuclear myopathies under attack: A plethora of therapeutic targets Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy

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P2860

Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice.

http://www.wikidata.org/entity/Q34756083

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Inhibition of activin receptor ...... n myotubularin-deficient mice.

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Inhibition of activin receptor ...... n myotubularin-deficient mice.

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Inhibition of activin receptor ...... n myotubularin-deficient mice.

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type

label

Inhibition of activin receptor ...... n myotubularin-deficient mice.

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Inhibition of activin receptor ...... n myotubularin-deficient mice.

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Inhibition of activin receptor ...... n myotubularin-deficient mice.

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Inhibition of activin receptor ...... n myotubularin-deficient mice.

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Inhibition of activin receptor ...... n myotubularin-deficient mice.

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Inhibition of activin receptor ...... n myotubularin-deficient mice.

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J.AJPATH.2010.10.035

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The American Journal of Pathology

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Inhibition of activin receptor ...... n myotubularin-deficient mice.

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Alan H Beggs

http://www.w3.org/2001/XMLSchema#string

Anna Buj-Bello

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Ariana Wermer-Colan

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Benjamin P Read

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Christopher R Pierson

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Jasbir S Seehra

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Jennifer L Lachey

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Matthew J Stein

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Michael W Lawlor

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Nicole Yang

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P2860

Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells

Regulation of muscle growth by multiple ligands signaling through activin type II receptors.

Regulation of myostatin activity and muscle growth

Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy.

Myostatin negatively regulates satellite cell activation and self-renewal

Loss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathy

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

X-linked myotubular and centronuclear myopathies

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy

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