Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy. - Wikidata - awgldk - TriplyDB

Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy.

Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy.

http://www.wikidata.org/entity/Q24647245

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Drug treatment for spinal muscular atrophy types II and III Drug treatment for spinal muscular atrophy types II and III Is spinal muscular atrophy a disease of the motor neurons only: pathogenesis and therapeutic implications?Subcutaneous administration of TC007 reduces disease severity in an animal model of SMA SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy Protective effects of butyrate-based compounds on a mouse model for spinal muscular atrophy.The effect of diet on the protective action of D156844 observed in spinal muscular atrophy mice.Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy Spinal muscular atrophy: new and emerging insights from model mice Spinal muscular atrophy: mechanisms and therapeutic strategies.Assays for the identification and prioritization of drug candidates for spinal muscular atrophy Therapeutic developments in spinal muscular atrophy.Molecular diagnosis of duchenne muscular dystrophy: past, present and future in relation to implementing therapies New therapeutic approaches to spinal muscular atrophy.SMN-inducing compounds for the treatment of spinal muscular atrophy.Antisense oligonucleotides for the treatment of spinal muscular atrophy.Spinal Muscular Atrophy Therapeutics: Where do we Stand?Evaluation of peripheral blood mononuclear cell processing and analysis for Survival Motor Neuron protein.Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy.Extracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass.Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice.Spinal muscular atrophy: from tissue specificity to therapeutic strategies Role of TGF-β signaling in inherited and acquired myopathies.Increasing expression and decreasing degradation of SMN ameliorate the spinal muscular atrophy phenotype in mice Bifunctional RNAs targeting the intronic splicing silencer N1 increase SMN levels and reduce disease severity in an animal model of spinal muscular atrophy The spinal muscular atrophy mouse model, SMAΔ7, displays altered axonal transport without global neurofilament alterations.A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients.The effect of the DcpS inhibitor D156844 on the protective action of follistatin in mice with spinal muscular atrophy.Neurogenic and myogenic contributions to hereditary motor neuron disease.Therapy development for spinal muscular atrophy in SMN independent targets.Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA.Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy.Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice Skeletal muscle in motor neuron diseases: therapeutic target and delivery route for potential treatments.Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agents Activin signaling as an emerging target for therapeutic interventions Association of the K153R polymorphism in the myostatin gene and extreme longevity.Spinal muscular atrophy: an update on therapeutic progress Inhibition of myostatin does not ameliorate disease features of severe spinal muscular atrophy mice.

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P2860

Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy.

http://www.wikidata.org/entity/Q24647245

description

2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Delivery of recombinant follis ...... del of spinal muscular atrophy

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Delivery of recombinant follis ...... el of spinal muscular atrophy.

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Delivery of recombinant follis ...... el of spinal muscular atrophy.

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type

label

Delivery of recombinant follis ...... del of spinal muscular atrophy

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Delivery of recombinant follis ...... el of spinal muscular atrophy.

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Delivery of recombinant follis ...... el of spinal muscular atrophy.

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prefLabel

Delivery of recombinant follis ...... del of spinal muscular atrophy

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Delivery of recombinant follis ...... el of spinal muscular atrophy.

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Delivery of recombinant follis ...... el of spinal muscular atrophy.

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Human Molecular Genetics

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Delivery of recombinant follis ...... el of spinal muscular atrophy.

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Christian L Lorson

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Ferrill F Rose

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Hansjörg Rindt

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Virginia B Mattis

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P2860

Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways

A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs

Myostatin mutation associated with gross muscle hypertrophy in a child

Regulation of myostatin activity and muscle growth

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

Novel aminoglycosides increase SMN levels in spinal muscular atrophy fibroblasts

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy

FLRG (follistatin-related gene), a new target of chromosomal rearrangement in malignant blood disorders

Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy.

Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains

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997-1005

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10.1093/HMG/DDN426

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6

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23655358

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19074460

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spinal muscular atrophy

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2649020

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