Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing. - Wikidata - awgldk - TriplyDB

Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing.

Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing.

http://www.wikidata.org/entity/Q34772017

about

Rational Protein Engineering Guided by Deep Mutational Scanning A novel platform for antibody library selection in mammalian cells based on a growth signalobody.Deep mutational scanning: a new style of protein science Domain structure of growth signalobodies critically affects the outcome of antibody library selection.Selection and characterization of the novel anti-human PD-1 FV78 antibody from a targeted epitope mammalian cell-displayed antibody library.Tuning the specificity of a Two-in-One Fab against three angiogenic antigens by fully utilizing the information of deep mutational scanning.A statistical framework for analyzing deep mutational scanning data.Affinity Maturation of a Cyclic Peptide Handle for Therapeutic Antibodies Using Deep Mutational Scanning.The power of multiplexed functional analysis of genetic variants.Deep sequencing methods for protein engineering and design.Measuring the sequence-affinity landscape of antibodies with massively parallel titration curves.High-Throughput Assays to Assess the Functional Impact of Genetic Variants: A Road Towards Genomic-Driven Medicine.Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.Hierarchical design of artificial proteins and complexes toward synthetic structural biology.Thermodynamic analyses of amino acid residues at the interface of an antibody B2212A and its antigen roundabout homolog 1.Next-Generation Sequencing of Antibody Display Repertoires.Mapping Interaction Sites on Human Chemokine Receptors by Deep Mutational Scanning.High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis Multiplexed assays of variant effects contribute to a growing genotype-phenotype atlas

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Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing.

http://www.wikidata.org/entity/Q34772017

description

2013 nî lūn-bûn

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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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Deep mutational scanning of an ...... ively parallel pyrosequencing.

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Deep mutational scanning of an ...... ively parallel pyrosequencing.

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Alexander V Ivanov

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Charles M Forsyth

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David B Powers

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Dixie Polakoff

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Jennifer Razo

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Keith Wilson

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Minhtam Doan

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Robert B DuBridge

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Veronica Juan

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Yoshiko Akamatsu

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P2860

Genome sequencing in microfabricated high-density picolitre reactors

A humanized antibody that binds to the interleukin 2 receptor

Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing

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Anatomy of hot spots in protein interfaces

Sequencing antibody repertoires: the next generation.

Whole IgG surface display on mammalian cells: Application to isolation of neutralizing chicken monoclonal anti-IL-12 antibodies.

High-throughput sequencing of the zebrafish antibody repertoire.

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire.

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523-532

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10.4161/MABS.24979

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4

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