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Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells.Shikonin Inhibits Inflammatory Response in Rheumatoid Arthritis Synovial Fibroblasts via lncRNA-NR024118.Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plantsShikonin increases glucose uptake in skeletal muscle cells and improves plasma glucose levels in diabetic Goto-Kakizaki ratsSensitizing the therapeutic efficacy of taxol with shikonin in human breast cancer cellsAcetylshikonin from Zicao Prevents Obesity in Rats on a High-Fat Diet by Inhibiting Lipid Accumulation and Inducing LipolysisQuinones from plants of northeastern Brazil: structural diversity, chemical transformations, NMR data and biological activities.Inhibitory effect of acetylshikonin on human gastric carcinoma cell line SGC-7901 in vitro and in vivo.The effects of Alkanna tinctoria Tausch on split-thickness skin graft donor site management: a randomized, blinded placebo-controlled trial.Anti-tumor effects of shikonin derivatives on human medullary thyroid carcinoma cells.Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling.β,β-Dimethylacrylshikonin sensitizes human colon cancer cells to ionizing radiation through the upregulation of reactive oxygen species.In vitro induction of erythrocyte phosphatidylserine translocation by the natural naphthoquinone shikonin.Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cellsExpression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston].The anti-proliferation effect of Aikete injection on hepatocellular carcinoma in vitro and in vivo.Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus.Inhibitory effects of β,β-dimethylacrylshikonin on hepatocellular carcinoma in vitro and in vivo.Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1Mechanisms behind the inhibition of lung adenocarcinoma cell by shikoninβ,β-Dimethylacrylshikonin induces mitochondria dependent apoptosis through ERK pathway in human gastric cancer SGC-7901 cells.Shikonin inhibits maturation of bone marrow-derived dendritic cells and suppresses allergic airway inflammation in a murine model of asthmaShikonin suppresses ERK 1/2 phosphorylation during the early stages of adipocyte differentiation in 3T3-L1 cells.Shikonin Induces Apoptosis, Necrosis, and Premature Senescence of Human A549 Lung Cancer Cells through Upregulation of p53 ExpressionShikonin protects chondrocytes from interleukin-1beta-induced apoptosis by regulating PI3K/Akt signaling pathwayHigh-throughput screen of natural product libraries for hsp90 inhibitors.Shikonin induces apoptosis in the human gastric cancer cells HGC-27 through mitochondria-mediated pathway.Single- and Repeat-dose Oral Toxicity Studies of Lithospermum erythrorhizon Extract in Dogs.Effect of shikonin on multidrug resistance in HepG2: The role of SIRT1.Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR-NF-κB signalling pathway in human epidermoid carcinoma A431 cells.The inhibitory effect of shikonin on the agonist-induced regulation of vascular contractility.Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibitionTargeting tumor proteasome with traditional Chinese medicine.Investigating the potential of Shikonin as a novel hypertrophic scar treatment.Shikonin enhances efficacy of a gene-based cancer vaccine via induction of RANTES.Shikonin reduces TGF-β1-induced collagen production and contraction in hypertrophic scar-derived human skin fibroblasts.Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1.Shikonin inhibits IFN-γ-induced K17 over-expression of HaCaT cells by interfering with STAT3 signaling.Inhibition of estrogen signaling activates the NRF2 pathway in breast cancer.The molecular basis of wound healing processes induced by lithospermi radix: a proteomics and biochemical analysis.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cellular pharmacology studies of shikonin derivatives.
@ast
Cellular pharmacology studies of shikonin derivatives.
@en
Cellular pharmacology studies of shikonin derivatives.
@nl
type
label
Cellular pharmacology studies of shikonin derivatives.
@ast
Cellular pharmacology studies of shikonin derivatives.
@en
Cellular pharmacology studies of shikonin derivatives.
@nl
prefLabel
Cellular pharmacology studies of shikonin derivatives.
@ast
Cellular pharmacology studies of shikonin derivatives.
@en
Cellular pharmacology studies of shikonin derivatives.
@nl
P2093
P2860
P356
P1476
Cellular pharmacology studies of shikonin derivatives
@en
P2093
Joost J Oppenheim
M Zack Howard
P2860
P304
P356
10.1002/PTR.1100
P50
P577
2002-05-01T00:00:00Z