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Robust Stimulation of W1282X-CFTR Channel Activity by a Combination of Allosteric ModulatorsInteraction non grata between CFTR's correctors and potentiatorsMolecular modelling and molecular dynamics of CFTR.Long-range coupling between the extracellular gates and the intracellular ATP binding domains of multidrug resistance protein pumps and cystic fibrosis transmembrane conductance regulator channelsOrkambi® and amplifier co-therapy improves function from a rare CFTR mutation in gene-edited cells and patient tissue.Revealing the activation pathway for TMEM16A chloride channels from macroscopic currents and kinetic models.Efficacy of lumacaftor-ivacaftor for the treatment of cystic fibrosis patients homozygous for the F508del-CFTR mutation.Structural Changes Fundamental to Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Pore.Facilitating Structure-Function Studies of CFTR Modulator Sites with Efficiencies in Mutagenesis and Functional Screening.Synergistic Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Gating by Two Chemically Distinct Potentiators, Ivacaftor (VX-770) and 5-Nitro-2-(3-Phenylpropylamino) Benzoate.On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator.External Zn(2+) binding to cysteine-substituted cystic fibrosis transmembrane conductance regulator constructs regulates channel gating and curcumin potentiation.CFTR potentiators: from bench to bedside.A common mechanism for CFTR potentiators.Structural mechanisms of CFTR function and dysfunction.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Modulation of CFTR gating by permeant ions.
@ast
Modulation of CFTR gating by permeant ions.
@en
Modulation of CFTR gating by permeant ions.
@nl
type
label
Modulation of CFTR gating by permeant ions.
@ast
Modulation of CFTR gating by permeant ions.
@en
Modulation of CFTR gating by permeant ions.
@nl
prefLabel
Modulation of CFTR gating by permeant ions.
@ast
Modulation of CFTR gating by permeant ions.
@en
Modulation of CFTR gating by permeant ions.
@nl
P2093
P2860
P356
P1476
Modulation of CFTR gating by permeant ions.
@en
P2093
Jiunn-Tyng Yeh
Tzyh-Chang Hwang
P2860
P356
10.1085/JGP.201411272
P577
2014-12-15T00:00:00Z