EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation.
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Preclinical Data on Efficacy of 10 Drug-Radiation Combinations: Evaluations, Concerns, and RecommendationsAfatinib, an Irreversible EGFR Family Inhibitor, Shows Activity Toward Pancreatic Cancer Cells, Alone and in Combination with Radiotherapy, Independent of KRAS Status.Prognostic value of tumor mutations in radically treated locally advanced non-small cell lung cancer patients.Adding Erlotinib to Chemoradiation Improves Overall Survival but Not Progression-Free Survival in Stage III Non-Small Cell Lung CancerRadiotherapy plus EGFR TKIs in non-small cell lung cancer patients with brain metastases: an update meta-analysis.Radiation oncology in vitro: trends to improve radiotherapy through molecular targets.Selumetinib for the treatment of non-small cell lung cancer.Adapting a drug screening platform to discover associations of molecular targeted radiosensitizers with genomic biomarkersImpact of EGFR mutations and KRAS amino acid substitution on the response to radiotherapy for brain metastasis of non-small-cell lung cancer.Connecting cancer biology and clinical outcomes to imaging in KRAS mutant and wild-type colorectal cancer liver tumors following selective internal radiation therapy with yttrium-90.Differential response to ablative ionizing radiation in genetically distinct non-small cell lung cancer cells.YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells.Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway.Metalloprotease-dependent activation of EGFR modulates CD44+/CD24- populations in triple negative breast cancer cells through the MEK/ERK pathway.Inhibition of GRP78 abrogates radioresistance in oropharyngeal carcinoma cells after EGFR inhibition by cetuximab.PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors.Phase II Study of Proton-Based Stereotactic Body Radiation Therapy for Liver Metastases: Importance of Tumor Genotype.PARP-1 inhibition with or without ionizing radiation confers reactive oxygen species-mediated cytotoxicity preferentially to cancer cells with mutant TP53.Towards an integrated understanding of epidermal growth factor receptor biology for radiation therapy: integrins enter.Expression levels of hnRNP K and p21WAF1/CIP1 are associated with resistance to radiochemotherapy independent of p53 pathway activation in rectal adenocarcinomaA pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomesGenomic mutations and histopathologic biomarkers in Y radioembolization for chemorefractory colorectal liver metastases
P2860
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P2860
EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@ast
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@en
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@nl
type
label
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@ast
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@en
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@nl
prefLabel
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@ast
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@en
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@nl
P2093
P2860
P1433
P1476
EGFR-mediated chromatin conden ...... ls against ionizing radiation.
@en
P2093
Anurag Singh
Ashley M Kern
Cyril H Benes
Dipanjan Chowdhury
Henning Willers
Jason A Efstathiou
Jeff Settleman
Marieke Hülskötter
Patricia Greninger
P2860
P304
P356
10.1158/0008-5472.CAN-13-3157
P407
P577
2014-03-19T00:00:00Z