Phospholipase D1 is an effector of Rheb in the mTOR pathway. - Wikidata - awgldk - TriplyDB

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

http://www.wikidata.org/entity/Q34786317

about

Regulation of TOR by small GTPases Spatial regulation of the mTORC1 system in amino acids sensing pathway The role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistance Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting Regulation of mTORC1 by PI3K signaling Multifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscle Lipid biology of breast cancer Age effect on myocellular remodeling: response to exercise and nutrition in humans The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling mTOR signaling in tumorigenesis mVps34 is activated following high-resistance contractions Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation Enhancing mTOR-targeted cancer therapy.TOR-dependent control of autophagy: biting the hand that feeds E2F1 regulates cellular growth by mTORC1 signaling.Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signaling Intracellular parasitism with Toxoplasma gondii stimulates mammalian-target-of-rapamycin-dependent host cell growth despite impaired signalling to S6K1 and 4E-BP1.Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic Beta cells.High-frequency electrically stimulated skeletal muscle contractions increase p70s6k phosphorylation independent of known IGF-I sensitive signaling pathways Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR)Recent progress in the study of the Rheb family GTPases.Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age.mTOR signaling for biological control and cancer.Rheb and Rags come together at the lysosome to activate mTORC1.Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex.Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.Growing knowledge of the mTOR signaling network.Negative regulation of mTOR activation by diacylglycerol kinases.Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s)Frontier of epilepsy research - mTOR signaling pathway.Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).Regulation of protein synthesis by amino acids in muscle of neonates.Reciprocal regulation of AMP-activated protein kinase and phospholipase D

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Phospholipase D1 is an effector of Rheb in the mTOR pathway.

http://www.wikidata.org/entity/Q34786317

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@ast

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@en

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@nl

type

label

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@ast

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@en

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@nl

prefLabel

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@ast

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@en

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

@nl

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PNAS.0712268105

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Phospholipase D1 is an effector of Rheb in the mTOR pathway

@en

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C Zhang

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F J Zwartkruis

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H A Brown

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J Chen

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M Armstrong

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M-S Yoon

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Y Fang

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Y Sun

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P2860

Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

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10.1073/PNAS.0712268105

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24

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105

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2008-06-11T00:00:00Z

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5305843

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18550814

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2448829

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