What goes on behind closed doors: physiological versus pharmacological steroid hormone actions.
about
Structures and mechanism for the design of highly potent glucocorticoidsPA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivationA model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activatorsSTAMP alters the growth of transformed and ovarian cancer cells.A theoretical framework for gene induction and experimental comparisons.Nongenomic signaling pathways of estrogen toxicity.HPA axis responsiveness to stress: implications for healthy aging.Deducing the temporal order of cofactor function in ligand-regulated gene transcription: theory and experimental verification.Glucocorticoid receptor cofactors as therapeutic targets.Impact of glucocorticoid receptor density on ligand-independent dimerization, cooperative ligand-binding and basal priming of transactivation: a cell culture model.A framework for modelling gene regulation which accommodates non-equilibrium mechanisms.Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors.The road less traveled: new views of steroid receptor action from the path of dose-response curves.Separate regions of glucocorticoid receptor, coactivator TIF2, and comodulator STAMP modify different parameters of glucocorticoid-mediated gene induction.Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathwaysKinetically Defined Mechanisms and Positions of Action of Two New Modulators of Glucocorticoid Receptor-regulated Gene Induction.Discovery of a highly potent glucocorticoid for asthma treatmentA conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties.Modulation of glucocorticoid receptor induction properties by cofactors in peripheral blood mononuclear cells.A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction.The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights.The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.Interaction of basal forebrain cholinergic neurons with the glucocorticoid system in stress regulation and cognitive impairment.Effects of acute and chronic administration of methylprednisolone on oxidative stress in rat lungs.An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics.Theory of partial agonist activity of steroid hormones.Mineralocorticoid Receptor (MR) trans-Activation of Inflammatory AP-1 Signaling: DEPENDENCE ON DNA SEQUENCE, MR CONFORMATION, AND AP-1 FAMILY MEMBER EXPRESSIONEffects of tamoxifen on estrogen receptor-α level in immune cells and humoral specific response after immunization of C3H/He male mice with syngeneic testicular germ cells (TGC).An Approach to Greater Specificity for Glucocorticoids.
P2860
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P2860
What goes on behind closed doors: physiological versus pharmacological steroid hormone actions.
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
What goes on behind closed doo ...... gical steroid hormone actions.
@ast
What goes on behind closed doo ...... gical steroid hormone actions.
@en
What goes on behind closed doo ...... gical steroid hormone actions.
@nl
type
label
What goes on behind closed doo ...... gical steroid hormone actions.
@ast
What goes on behind closed doo ...... gical steroid hormone actions.
@en
What goes on behind closed doo ...... gical steroid hormone actions.
@nl
prefLabel
What goes on behind closed doo ...... gical steroid hormone actions.
@ast
What goes on behind closed doo ...... gical steroid hormone actions.
@en
What goes on behind closed doo ...... gical steroid hormone actions.
@nl
P2860
P356
P1433
P1476
What goes on behind closed doo ...... gical steroid hormone actions.
@en
P2093
S Stoney Simons
P2860
P304
P356
10.1002/BIES.20792
P407
P577
2008-08-01T00:00:00Z