Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart
about
Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cellsElevated expression of the metabolic regulator receptor-interacting protein 140 results in cardiac hypertrophy and impaired cardiac functionMitochondrial biogenesis and dynamics in the developing and diseased heartMitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer TherapyMitochondrial dysfunction in heart failureNew insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyondTranscriptional integration of mitochondrial biogenesisPGC-1 proteins and heart failureRole of mitochondria in nonalcoholic fatty liver diseaseRosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1αHypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolismPGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.Mitochondria in heart failureRegulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stressPPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1Lipidomics for studying metabolismHeart Failure in Pediatric Patients With Congenital Heart Disease.Targeting mitochondrial dysfunction in the treatment of heart failure.Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscleCardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis.Cancer therapy-induced cardiotoxicity: basic mechanisms and potential cardioprotective therapies.Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity.Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α.Dynamic regulation of genes involved in mitochondrial DNA replication and transcription during mouse brown fat cell differentiation and recruitment.The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signallingPGC-1 coactivator activity is required for murine erythropoiesis.Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsisRescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activatorsA role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growthMyc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice.The role of PGC-1 coactivators in aging skeletal muscle and heart.Defective DNA replication impairs mitochondrial biogenesis in human failing heartsHypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function.A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsisGABP transcription factor (nuclear respiratory factor 2) is required for mitochondrial biogenesis.Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory networkTelomere dysfunction induces metabolic and mitochondrial compromise.Saturated fats: a perspective from lactation and milk compositionIdentification of the molecular basis of doxorubicin-induced cardiotoxicity.Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding.
P2860
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P2860
Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Transcriptional coactivators P ...... inatal maturation of the heart
@ast
Transcriptional coactivators P ...... inatal maturation of the heart
@en
Transcriptional coactivators P ...... inatal maturation of the heart
@nl
type
label
Transcriptional coactivators P ...... inatal maturation of the heart
@ast
Transcriptional coactivators P ...... inatal maturation of the heart
@en
Transcriptional coactivators P ...... inatal maturation of the heart
@nl
prefLabel
Transcriptional coactivators P ...... inatal maturation of the heart
@ast
Transcriptional coactivators P ...... inatal maturation of the heart
@en
Transcriptional coactivators P ...... inatal maturation of the heart
@nl
P2093
P2860
P356
P1433
P1476
Transcriptional coactivators P ...... inatal maturation of the heart
@en
P2093
Attila Kovacs
Christoph Zechner
Daniel P Flanagan
Daniel P Kelly
Denis M Medeiros
Paul J Schaeffer
Sean M Kelly
Teresa C Leone
P2860
P304
P356
10.1101/GAD.1661708
P577
2008-07-01T00:00:00Z