An early response transcription factor, Egr-1, enhances insulin resistance in type 2 diabetes with chronic hyperinsulinism
about
Systems biology approach reveals genome to phenome correlation in type 2 diabetesInsulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathwayExploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis.Identification of transcription factors potentially involved in human adipogenesis in vitroEmerging roles of zinc finger proteins in regulating adipogenesisEarly growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity.Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in miceInsulin-response epigenetic activation of Egr-1 and JunB genes at the nuclear periphery by A-type lamin-associated pY19-Caveolin-2 in the inner nuclear membrane.Fetoplacental vascular endothelial dysfunction as an early phenomenon in the programming of human adult diseases in subjects born from gestational diabetes mellitus or obesity in pregnancy.GGPPS, a new EGR-1 target gene, reactivates ERK 1/2 signaling through increasing Ras prenylation.4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGLLipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway.Comorbidities of Psoriasis - Exploring the Links by Network Approach.EGR1 regulates hepatic clock gene amplitude by activating Per1 transcription.Dietary obesity-induced Egr-1 in adipocytes facilitates energy storage via suppression of FOXC2.Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity.Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection.Protein prenylation and human diseases: a balance of protein farnesylation and geranylgeranylation.Recent Advances in the Development of Mammalian Geranylgeranyl Diphosphate Synthase Inhibitors.The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure.Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes.Effects of intravitreal insulin and insulin signaling cascade inhibitors on emmetropization in the chick.Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma.Molecular pathways reflecting poor intrauterine growth are found in Wharton's jelly-derived mesenchymal stem cells.GGPPS-mediated Rab27A geranylgeranylation regulates β cell dysfunction during type 2 diabetes development by affecting insulin granule docked pool formation.
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P2860
An early response transcription factor, Egr-1, enhances insulin resistance in type 2 diabetes with chronic hyperinsulinism
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
An early response transcriptio ...... s with chronic hyperinsulinism
@ast
An early response transcriptio ...... s with chronic hyperinsulinism
@en
An early response transcriptio ...... s with chronic hyperinsulinism
@nl
type
label
An early response transcriptio ...... s with chronic hyperinsulinism
@ast
An early response transcriptio ...... s with chronic hyperinsulinism
@en
An early response transcriptio ...... s with chronic hyperinsulinism
@nl
prefLabel
An early response transcriptio ...... s with chronic hyperinsulinism
@ast
An early response transcriptio ...... s with chronic hyperinsulinism
@en
An early response transcriptio ...... s with chronic hyperinsulinism
@nl
P2093
P2860
P356
P1476
An early response transcriptio ...... s with chronic hyperinsulinism
@en
P2093
P2860
P304
14508-14515
P356
10.1074/JBC.M110.190165
P407
P577
2011-02-14T00:00:00Z