An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
about
Calcium input frequency, duration and amplitude differentially modulate the relative activation of calcineurin and CaMKIIScalable rule-based modelling of allosteric proteins and biochemical networksComputing phenomenologic Adair-Klotz constants from microscopic MWC parametersModeling intracellular signaling underlying striatal function in health and diseaseQuantitative and logic modelling of molecular and gene networksA dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase IIStructural analysis and stochastic modelling suggest a mechanism for calmodulin trapping by CaMKIITransfer functions for protein signal transduction: application to a model of striatal neural plasticityIntegration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatumNeurogranin targets calmodulin and lowers the threshold for the induction of long-term potentiationOptimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRETA new multicompartmental reaction-diffusion modeling method links transient membrane attachment of E. coli MinE to E-ring formation.STEPS: Modeling and Simulating Complex Reaction-Diffusion Systems with Python.Ligand depletion in vivo modulates the dynamic range and cooperativity of signal transduction.Lobe specific Ca2+-calmodulin nano-domain in neuronal spines: a single molecule level analysis.Relationships between structural dynamics and functional kinetics in oligomeric membrane receptorsModulation of calmodulin lobes by different targets: an allosteric model with hemiconcerted conformational transitionsKinetic regulation of multi-ligand binding proteins.Modelling intracellular competition for calcium: kinetic and thermodynamic control of different molecular modes of signal decodingStochastic Induction of Long-Term Potentiation and Long-Term DepressionNeuroimmunomodulation by calcineurin in aging and Alzheimer's disease.A role for calcineurin in Alzheimer's disease.Dysregulation of neuronal calcium homeostasis in Alzheimer's disease - A therapeutic opportunity?Calmodulin transduces Ca2+ oscillations into differential regulation of its target proteinsPostsynaptic signal transduction models for long-term potentiation and depression.Cooperative binding mitigates the high-dose hook effect.Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium.Effects of intrahippocampal administration of the phosphatase inhibitor okadaic acid: Dual effects on memory formation.Biophysical attributes that affect CaMKII activation deduced with a novel spatial stochastic simulation approach.Opposing Intermolecular Tuning of Ca2+ Affinity for Calmodulin by Neurogranin and CaMKII Peptides.FindSim: A Framework for Integrating Neuronal Data and Signaling Models.Bile composition, plasma lipids and oxidative hepatic damage induced by calcium supplementation; effects of goat or cow milk consumption
P2860
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P2860
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@ast
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@en
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@nl
type
label
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@ast
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@en
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@nl
prefLabel
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@ast
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@en
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@nl
P2860
P356
P1476
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
@en
P2093
Stuart J Edelstein
P2860
P304
10768-10773
P356
10.1073/PNAS.0804672105
P407
P577
2008-07-31T00:00:00Z