Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2 - Wikidata - awgldk - TriplyDB

Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

http://www.wikidata.org/entity/Q34804981

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Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?Pathway-selective insulin resistance and metabolic disease: the importance of nutrient flux Finding needles in a haystack: application of network analysis and target enrichment studies for the identification of potential anti-diabetic phytochemicals Mechanisms for insulin resistance: common threads and missing links Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice.Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans.Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice The Role of INDY in Metabolic Regulation Steatosis inhibits liver cell store-operated Ca²⁺ entry and reduces ER Ca²⁺ through a protein kinase C-dependent mechanism.Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice.FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis.OXPHOS-Mediated Induction of NAD+ Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease.Treatment of rats with Jiangzhi Capsule improves liquid fructose-induced fatty liver: modulation of hepatic expression of SREBP-1c and DGAT-2.The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes Diacylglycerol activation of protein kinase Cε and hepatic insulin resistance.Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signaling Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5)Muscle-specific vascular endothelial growth factor deletion induces muscle capillary rarefaction creating muscle insulin resistance.Second-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance.Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects.Cellular mechanism by which estradiol protects female ovariectomized mice from high-fat diet-induced hepatic and muscle insulin resistance.Restoration of euglycemia after duodenal bypass surgery is reliant on central and peripheral inputs in Zucker fa/fa rats.Coordinated regulation of hepatic energy stores by leptin and hypothalamic agouti-related protein CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism.Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes.Inputs and outputs of insulin receptor.The Addition of Liquid Fructose to a Western-Type Diet in LDL-R-/- Mice Induces Liver Inflammation and Fibrogenesis Markers without Disrupting Insulin Receptor Signalling after an Insulin Challenge Dissociating fatty liver and diabetes The tail wagging the dog--regulation of lipid metabolism by protein kinase C.n-3 Polyunsaturated fatty acids modulate metabolism of insulin-sensitive tissues: implication for the prevention of type 2 diabetes.Intracellular lipid accumulation and shift during diabetes progression.XBP1s Is an Anti-lipogenic Protein.Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance.Non-alcoholic Fatty Liver Disease: Beneficial Effects of Flavonoids.Hepatitis C virus nonstructural protein 5A favors upregulation of gluconeogenic and lipogenic gene expression leading towards insulin resistance: a metabolic syndrome.Lipid droplets and liver disease: from basic biology to clinical implications.Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides and de novo synthesized fatty acids in HepG2 cells.Trivalent chromium alleviates oleic acid induced steatosis in SMMC-7721 cells by decreasing fatty acid uptake and triglyceride synthesis.

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Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

http://www.wikidata.org/entity/Q34804981

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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PNAS.1103451108

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Proceedings of the National Academy of Sciences of the United States of America

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Hepatic insulin resistance in ...... acylglycerol acyltransferase 2

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Andreas L Birkenfeld

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Blas A Guigni

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Debbie C Jiang

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Dongyan Zhang

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François R Jornayvaz

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Hui-Young Lee

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Michael J Jurczak

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Shoichi Kanda

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Varman T Samuel

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Inflammation and metabolic disorders

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance

Nonalcoholic fatty liver disease

Cellular mechanisms of insulin resistance

Nutritional modulation of nonalcoholic fatty liver disease and insulin resistance: human data.

Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanisms

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5748-5752

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scholarly article

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10.1073/PNAS.1103451108

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14

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108

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Gerald I. Shulman

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2011-03-21T00:00:00Z

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50850451

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21436037

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3078388

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