Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
about
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusionReporter-Expressing, Replicating-Competent Recombinant ArenavirusesReplication-Competent Influenza A Viruses Expressing Reporter GenesNanoparticles as potential new generation broad spectrum antimicrobial agentsCuring a viral infection by targeting the host: the example of cyclophilin inhibitorsBroad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.SAR-Based Optimization of a 4-Quinoline Carboxylic Acid Analogue with Potent Antiviral ActivityThe Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignEmerging Roles of Protein Deamidation in Innate Immune SignalingA novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferonInhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunityDiscovery of potent broad spectrum antivirals derived from marine actinobacteriaChemical derivatives of a small molecule deubiquitinase inhibitor have antiviral activity against several RNA virusesThe combination effects of licl and the active leflunomide metabolite, A771726, on viral-induced interleukin 6 production and EV-A71 replicationBroad-spectrum agents for flaviviral infections: dengue, Zika and beyondA Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin ProteinA Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity In VitroThe influenza virus NS1 protein as a therapeutic target.T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitroIdentification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus.High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses.Postinfection A77-1726 treatment improves cardiopulmonary function in H1N1 influenza-infected miceIdentification of small molecules with type I interferon inducing properties by high-throughput screening.Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.Systematic review: current concepts and challenges for the direct-acting antiviral era in hepatitis C cirrhosis.Cytomegalovirus-mediated activation of pyrimidine biosynthesis drives UDP-sugar synthesis to support viral protein glycosylationReplication-competent influenza A viruses expressing a red fluorescent protein.[Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening].Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1.Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)Permissive and restricted virus infection of murine embryonic stem cells.Development of novel entry inhibitors targeting emerging viruses.Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virusCross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication.Reverse Genetics Approaches to Control Arenavirus.An unhealthy relationship: viral manipulation of the nuclear receptor superfamily.Manipulation of adenovirus interactions with host factors for gene therapy applications.Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export.
P2860
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P2860
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@ast
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@en
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@nl
type
label
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@ast
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@en
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@nl
prefLabel
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@ast
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@en
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@nl
P2860
P50
P356
P1476
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
@en
P2093
Andrea Kunz
Hans-Heinrich Hoffmann
P2860
P304
P356
10.1073/PNAS.1101143108
P407
P577
2011-03-21T00:00:00Z