Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
about
DNA resection in eukaryotes: deciding how to fix the breakDNA end resection: many nucleases make light workATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorManaging Single-Stranded DNA during Replication Stress in Fission YeastInhibition of the mitotic exit network in response to damaged telomeres.Survival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9.Unligated Okazaki Fragments Induce PCNA Ubiquitination and a Requirement for Rad59-Dependent Replication Fork Progression.Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctionsPhosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.A proteome-wide analysis of kinase-substrate network in the DNA damage response.Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switchMre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.The extent of error-prone replication restart by homologous recombination is controlled by Exo1 and checkpoint proteins.Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.14-3-3 Proteins regulate exonuclease 1-dependent processing of stalled replication forksTo fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres?Regulation of homologous recombination in eukaryotes.An mre11 mutation that promotes telomere recombination and an efficient bypass of senescence.The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.The UL12 protein of herpes simplex virus 1 is regulated by tyrosine phosphorylationCheckpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiaePif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.Rad9 interacts with Aft1 to facilitate genome surveillance in fragile genomic sites under non-DNA damage-inducing conditions in S. cerevisiaeRPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycleMec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends.The DNA damage checkpoint allows recombination between divergent DNA sequences in budding yeast.Sumoylation influences DNA break repair partly by increasing the solubility of a conserved end resection protein.Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.Exo1 phosphorylation status controls the hydroxyurea sensitivity of cells lacking the Pol32 subunit of DNA polymerases delta and zeta14-3-3 proteins restrain the Exo1 nuclease to prevent overresection.Differential genetic interactions between Sgs1, DNA-damage checkpoint components and DNA repair factors in the maintenance of chromosome stability.Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2.Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions.Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif.Human exonuclease 1 (EXO1) activity characterization and its function on flap structures.Sumoylation regulates EXO1 stability and processing of DNA damage.Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 PhosphataseSystematic Analysis of the DNA Damage Response Network in Telomere Defective Budding YeastControlling DNA-end resection: a new task for CDKs.
P2860
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P2860
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@ast
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@en
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@nl
type
label
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@ast
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@en
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@nl
prefLabel
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@ast
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@en
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@nl
P2093
P2860
P356
P1433
P1476
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
@en
P2093
Amanda Greenall
David Lydall
Hien-Ping Ngo
Isabelle Morin
Mikhajlo K Zubko
Nick Morrice
P2860
P304
P356
10.1038/EMBOJ.2008.171
P407
P577
2008-08-28T00:00:00Z