The interaction of DNA mismatch repair proteins with human exonuclease I
about
Human exonuclease I is required for 5' and 3' mismatch repairMolecular interactions of human Exo1 with DNACharacterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNAHuman MUS81 complexes stimulate flap endonuclease 1hMSH4-hMSH5 adenosine nucleotide processing and interactions with homologous recombination machineryTip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathwayFunctional residues on the surface of the N-terminal domain of yeast Pms1Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease FamilyNew insights into the mechanism of DNA mismatch repairThe exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome proteinInactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterilityDNA mismatch repair and mutation avoidance pathwaysAberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancerCharacterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctionsAltered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant micePartial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein AEmbryonic lethality after combined inactivation of Fancd2 and Mlh1 in mice.Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1.Hydrolytic function of Exo1 in mammalian mismatch repair.hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair.Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair.MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells.The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome.Analysis of conditional mutations in the Saccharomyces cerevisiae MLH1 gene in mismatch repair and in meiotic crossing over.Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage responseAn activation force-based affinity measure for analyzing complex networks.Exo1 phosphorylation status controls the hydroxyurea sensitivity of cells lacking the Pol32 subunit of DNA polymerases delta and zetaDifferential genetic interactions between Sgs1, DNA-damage checkpoint components and DNA repair factors in the maintenance of chromosome stability.Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1)Single-molecule imaging reveals the mechanism of Exo1 regulation by single-stranded DNA binding proteins.Human exonuclease 1 (EXO1) activity characterization and its function on flap structures.Mismatch repairHuman DNA mismatch repair: coupling of mismatch recognition to strand-specific excisionVisualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates.The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response.Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents.ATR-dependent pathways control hEXO1 stability in response to stalled forks.DNA-damage repair; the good, the bad, and the ugly.A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair.
P2860
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P2860
The interaction of DNA mismatch repair proteins with human exonuclease I
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The interaction of DNA mismatch repair proteins with human exonuclease I
@ast
The interaction of DNA mismatch repair proteins with human exonuclease I
@en
The interaction of DNA mismatch repair proteins with human exonuclease I
@en-gb
The interaction of DNA mismatch repair proteins with human exonuclease I
@nl
type
label
The interaction of DNA mismatch repair proteins with human exonuclease I
@ast
The interaction of DNA mismatch repair proteins with human exonuclease I
@en
The interaction of DNA mismatch repair proteins with human exonuclease I
@en-gb
The interaction of DNA mismatch repair proteins with human exonuclease I
@nl
prefLabel
The interaction of DNA mismatch repair proteins with human exonuclease I
@ast
The interaction of DNA mismatch repair proteins with human exonuclease I
@en
The interaction of DNA mismatch repair proteins with human exonuclease I
@en-gb
The interaction of DNA mismatch repair proteins with human exonuclease I
@nl
P2093
P2860
P921
P356
P1476
The interaction of DNA mismatch repair proteins with human exonuclease I
@en
P2093
P2860
P304
P356
10.1074/JBC.M102670200
P407
P577
2001-08-31T00:00:00Z