Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b.
about
The miR-200 and miR-221/222 microRNA families: opposing effects on epithelial identityEMT and stem cell-like properties associated with HIF-2α are involved in arsenite-induced transformation of human bronchial epithelial cellsInfluence of toxicologically relevant metals on human epigenetic regulationThe microRNA-200 family: small molecules with novel roles in cancer development, progression and therapyRepression of miR-143 mediates Cr (VI)-induced tumor angiogenesis via IGF-IR/IRS1/ERK/IL-8 pathwayArsenic-Associated Changes to the Epigenome: What Are the Functional Consequences?Arsenic responsive microRNAs in vivo and their potential involvement in arsenic-induced oxidative stressIncorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: strategies and challengesArsenic, asbestos and radon: emerging players in lung tumorigenesisArsenic exposure and the induction of human cancersAkt activation is responsible for enhanced migratory and invasive behavior of arsenic-transformed human bronchial epithelial cellsMolecular features in arsenic-induced lung tumorsChronic arsenic exposure and angiogenesis in human bronchial epithelial cells via the ROS/miR-199a-5p/HIF-1α/COX-2 pathwayAnalysis of the transcriptome in molecular epidemiology studiesArsenite promotes intestinal tumor cell proliferation and invasion by stimulating epithelial-to-mesenchymal transitionMicroRNA-200b suppresses arsenic-transformed cell migration by targeting protein kinase Cα and Wnt5b-protein kinase Cα positive feedback loop and inhibiting Rac1 activationMicroRNA-200b targets protein kinase Cα and suppresses triple-negative breast cancer metastasisAltered miRNA expression profiles and miR-1a associated with urethane-induced pulmonary carcinogenesis.Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use.Induction of human squamous cell-type carcinomas by arsenic.ERK5 negatively regulates tobacco smoke-induced pulmonary epithelial-mesenchymal transition.Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation.Epithelial to mesenchymal transition in arsenic-transformed cells promotes angiogenesis through activating β-catenin-vascular endothelial growth factor pathway.Induction of an EMT-like transformation and MET in vitro.Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions.Genetic and epigenetic effects of environmental arsenicals.Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis.MicroRNAs and lung cancers: from pathogenesis to clinical implicationsThe role of microRNAs in metal carcinogen-induced cell malignant transformation and tumorigenesis.A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment.Effects of arsenic toxicity beyond epigenetic modifications.MicroRNA-200c plays an oncogenic role in nasopharyngeal carcinoma by targeting PTEN.Nanomaterial and toxicity: what can proteomics tell us about the nanotoxicology?NF-κB-mediated inflammation leading to EMT via miR-200c is involved in cell transformation induced by cigarette smoke extract.EMT and CSC-like properties mediated by the IKKβ/IκBα/RelA signal pathway via the transcriptional regulator, Snail, are involved in the arsenite-induced neoplastic transformation of human keratinocytes.MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol.Curcumin reversed chronic tobacco smoke exposure induced urocystic EMT and acquisition of cancer stem cells properties via Wnt/β-catenin.Upregulation of histone-lysine methyltransferases plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation.Epigenetic Applications in Adverse Outcome Pathways and Environmental Risk Evaluation.Amelioration of arsenic-induced oxidative stress in CHO cells by flower extract
P2860
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P2860
Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@ast
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@en
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@nl
type
label
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@ast
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@en
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@nl
prefLabel
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@ast
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@en
Reversal and prevention of ars ...... ansformation by microRNA-200b.
@nl
P2093
P2860
P50
P356
P1476
Reversal and prevention of ars ...... ransformation by microRNA-200b
@en
P2093
Chengfeng Yang
Thomas Brabletz
Zhishan Wang
P2860
P304
P356
10.1093/TOXSCI/KFR029
P577
2011-02-02T00:00:00Z