Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.
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MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancerWithaferin-A--A Natural Anticancer Agent with Pleitropic Mechanisms of ActionWithaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signalingWithania somnifera root extract inhibits mammary cancer metastasis and epithelial to mesenchymal transitionVimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studiesWithaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivoWithaferin A inhibits the proteasome activity in mesothelioma in vitro and in vivoWithaferin a alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cellsWithaferin A Analogs That Target the AAA+ Chaperone p97.Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma.Withaferin A inhibits experimental epithelial-mesenchymal transition in MCF-10A cells and suppresses vimentin protein level in vivo in breast tumors.Mammary cancer chemoprevention by withaferin A is accompanied by in vivo suppression of self-renewal of cancer stem cellsWithaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated with withaferin a-induced apoptosis in MCF-7 breast cancer cellsNotch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis.Dihydroarteminsin-induced apoptosis is not dependent on the translocation of Bim to the endoplasmic reticulum in human lung adenocarcinoma cells.Withaferin A induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells.Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells.Withaferin A synergizes the therapeutic effect of doxorubicin through ROS-mediated autophagy in ovarian cancerTumor necrosis factor-α sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosisDinoxin B, a withanolide from Datura inoxia leaves with specific cytotoxic activities.Synthesis and proteasome inhibition of lithocholic acid derivativesAyurvedic medicine constituent withaferin a causes G2 and M phase cell cycle arrest in human breast cancer cellsWithaferin A targets heat shock protein 90 in pancreatic cancer cells.Evaluating the evidence for targeting FOXO3a in breast cancer: a systematic review.Withaferin a suppresses estrogen receptor-α expression in human breast cancer cellsOxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide Withaferin ATargeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer.Synergistic cytotoxic action of cisplatin and withaferin A on ovarian cancer cell lines.Short-form RON overexpression augments benzyl isothiocyanate-induced apoptosis in human breast cancer cellsThe Daniel K. Inouye College of Pharmacy Scripts: Poha Berry (Physalis peruviana) with Potential Anti-inflammatory and Cancer Prevention ActivitiesMulti-layer polymeric implants for sustained release of chemopreventives.Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cellsWithaferin A-induced apoptosis in human breast cancer cells is associated with suppression of inhibitor of apoptosis family protein expressionPS341 inhibits hepatocellular and colorectal cancer cells through the FOXO3/CTNNB1 signaling pathway.Withaferin A inhibits in vivo growth of breast cancer cells accelerated by Notch2 knockdown.Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways.Withania somnifera: From prevention to treatment of cancer
P2860
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P2860
Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@ast
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@en
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@nl
type
label
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@ast
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@en
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@nl
prefLabel
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@ast
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@en
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@nl
P2093
P2860
P1433
P1476
Withaferin A causes FOXO3a- an ...... n breast cancer cells in vivo.
@en
P2093
Eun-Ryeong Hahm
Renaud Warin
Shivendra V Singh
P2860
P304
P356
10.1158/0008-5472.CAN-08-1510
P407
P577
2008-09-01T00:00:00Z