Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells - Wikidata - awgldk - TriplyDB

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

http://www.wikidata.org/entity/Q36328445

about

Vimentin, colon cancer progression and resistance to butyrate and other HDACis Withaferin-A--A Natural Anticancer Agent with Pleitropic Mechanisms of Action A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.Withaferin A inhibits experimental epithelial-mesenchymal transition in MCF-10A cells and suppresses vimentin protein level in vivo in breast tumors.Type II Endometrial Cancer Overexpresses NILCO: A Preliminary Evaluation.Mammary cancer chemoprevention by withaferin A is accompanied by in vivo suppression of self-renewal of cancer stem cells Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells Targeting Notch Signaling in Colorectal Cancer.Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell.Anticancer activities of Withania somnifera: Current research, formulations, and future perspectives.Withaferin A inhibits in vivo growth of breast cancer cells accelerated by Notch2 knockdown.Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model.Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.Molecular targets and mechanisms of cancer prevention and treatment by withaferin a, a naturally occurring steroidal lactone.Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin.Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells Pharmacologic overview of Withania somnifera, the Indian Ginseng.Withaferin A protects against spinal cord injury by inhibiting apoptosis and inflammation in mice.Natural Withanolides in the Treatment of Chronic Diseases.Myeloid-derived suppressor cell function is reduced by Withaferin A, a potent and abundant component of Withania somnifera root extract.Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A.Molecular docking, QSAR and ADMET studies of withanolide analogs against breast cancer Withaferin A, a steroidal lactone from Withania somnifera, induces mitotic catastrophe and growth arrest in prostate cancer cells Peptidyl-prolyl cis/trans isomerase Pin1 regulates withaferin A-mediated cell cycle arrest in human breast cancer cells.

P2860

Q26748816-5493DE6A-DB8B-48B4-919C-D6FD9246C07E Q26766956-52D2DDB0-69CC-4D8C-AA30-A8B119E6BE04 Q28543036-2021AB9B-EC81-4C8E-939E-B42B73561DFC Q33563815-E698586B-0EC5-416E-B9D6-C31786817C9C Q33690570-585B096F-6D55-41FE-93EE-A75E15FAEA2C Q33808855-271129A9-E5D4-4A71-99FC-1EC54C166C94 Q33853018-D313405F-FE3E-4E76-A295-D00D2403939B Q34072980-484FDF76-1BC2-4126-8574-92C0F4B61C13 Q34482399-3436E8F0-A73B-49D5-AACA-320907E41D54 Q34483726-318A3E0B-EFEE-402F-9C89-6977037B5708 Q35595569-C8FB1CA4-79E7-44D9-A88A-407AB0F3DB7A Q36901996-B08E392A-AE3A-4653-A54C-31095CE0D553 Q37075399-D2EEFF68-94D0-42EF-9B85-F87030895D29 Q37384594-586549CE-1F51-4F0D-AD2B-F42F18DBA507 Q37469387-DA0E25AB-7AEC-424D-824B-39F937C754F7 Q37488585-B0298B85-E6F4-4D11-B4E0-CF9DB377211F Q37548974-F1550B52-7137-4C7E-8116-CE609C3540A0 Q38573788-8A222B2C-C414-4CC9-8C9D-D086254BC02D Q38715361-1F81D238-6EA5-4004-826E-987880E853BB Q38965226-71020716-D041-4A5C-9F38-3DFE363F62DA Q39104155-E168EB93-3561-4D9C-AB71-36C872DC3A01 Q40389234-EE37E136-5B57-4B8D-BEEA-8977EDF00C9B Q40997589-E173B429-DDBB-4604-AC39-6EEAF0BA5955 Q41916362-DA6698F7-A4C3-44AF-911D-9329C68EBC2D Q52722757-6993EAE5-D97F-4FE4-957D-C2718FE78715

P2860

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

http://www.wikidata.org/entity/Q36328445

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

@ast

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

@en

type

label

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

@ast

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

@en

prefLabel

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

@ast

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

@en

P1433

Q36328445-1B84598A-3651-46C9-8DB2-E460AF16A106

P1476

Q36328445-8F3109E0-9793-4A1C-8389-DCB20CE95E22

P2093

Q36328445-0E181982-FB63-4DD0-A956-6958B9FD890E

Q36328445-9550AFAB-0384-486F-AE1D-3DAED178D617

Q36328445-F3086D16-100C-49BA-A2C5-AC46B9F970B1

P2860

Q36328445-037C652E-4E12-4B30-B50E-87216DA553E1

Q36328445-075ECD36-1E88-4349-80D1-A5604E28EFB3

Q36328445-0A02D37C-EBC4-4D30-8B41-D8BDBEA90966

Q36328445-151ECB4F-4BDE-44BF-B0BE-3EB7F545C425

Q36328445-1D8C0323-055E-471E-913F-FBA55D2EE5A4

Q36328445-2385E75F-92FA-45E2-8571-175E92FCFBAF

Q36328445-2522D41A-AF70-4A08-A30B-A62D1126BE10

Q36328445-2C70E7FF-4123-4B02-9ECD-EF69BF7DBB7F

Q36328445-2F5A0A6D-94A5-4D08-97C6-D28BABF10875

Q36328445-4A0D88CB-9A49-46BA-BF15-73EFB172E8F7

P2888

Q36328445-DB8FD5A3-EFD0-4592-9471-78AD845C151E

P304

Q36328445-5E1F6295-68DB-4C93-B39F-542340053EF9

P31

Q36328445-7DD0CD7A-0B0E-407B-B112-75C46F5704D5

P356

Q36328445-3C6B3664-661C-4DB2-B732-32F8D521F0E3

P407

Q36328445-44157D3E-FB85-4AB9-9517-1DE6D6DBFA1F

P433

Q36328445-52618B55-0412-43DF-BCDB-07E7A5B0E0E6

P478

Q36328445-A72CAA48-07D2-4166-B3B9-669AE5F23260

P577

Q36328445-EED8165A-BACF-4614-8324-98CB1A3B0010

P698

Q36328445-A3FFE74E-F50B-43EB-B399-3D01A34C49E7

P932

Q36328445-FDC10F41-2151-43D2-A3CD-56AC752EBE80

P356

S10549-012-2239-6

P1433

Breast Cancer Research and Treatment

P1476

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

@en

P2093

Anuradha Sehrawat

http://www.w3.org/2001/XMLSchema#string

Joomin Lee

http://www.w3.org/2001/XMLSchema#string

Shivendra V Singh

http://www.w3.org/2001/XMLSchema#string

P2860

Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

Roots of Withania somnifera Inhibit Forestomach and Skin Carcinogenesis in Mice

Cancer statistics, 2010

Notch signaling: from the outside in

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

High-level JAG1 mRNA and protein predict poor outcome in breast cancer

Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect.

Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.

P2888

s10549-012-2239-6

P304

45-56

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S10549-012-2239-6

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

136

http://www.w3.org/2001/XMLSchema#string

P577

2012-09-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

22965833

http://www.w3.org/2001/XMLSchema#string

P932

3474857

http://www.w3.org/2001/XMLSchema#string