Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury. - Wikidata - awgldk - TriplyDB

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

http://www.wikidata.org/entity/Q34830891

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Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in the hemorrhagic brain Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia Misoprostol Reverse Hippocampal Neuron Cyclooxygenase-2 Downstream Signaling Imbalance in Aluminum-Overload Rats.Microsomal prostaglandin E synthase-1 and cyclooxygenase-2 are both required for ischaemic excitotoxicity Prostaglandin E2 synthases in neurologic homeostasis and disease Novel human mPGES-1 inhibitors identified through structure-based virtual screening.Microsomal prostaglandin E synthase-1 contributes to ischaemic excitotoxicity through prostaglandin E2 EP3 receptors.Phospholipase A2 superfamily members play divergent roles after spinal cord injury.The effects of increasing PGE2 on translocation of labeled albumin into rat brain.mPGES-1-derived PGE2 mediates dehydration natriuresis Cyclooxygenase-2 deficiency enhances Th2 immune responses and impairs neutrophil recruitment in hepatic ischemia/reperfusion injury Defective generation of a humoral immune response is associated with a reduced incidence and severity of collagen-induced arthritis in microsomal prostaglandin E synthase-1 null mice.Cardiovascular Consequences of Prostanoid I Receptor Deletion in Microsomal Prostaglandin E Synthase-1-Deficient Hyperlipidemic Mice.Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease.Reduced T cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice is mediated by nonhematopoietic cells.Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis.Prostaglandin E(2) synthase inhibition as a therapeutic target.Lipoprotein receptor-related protein-6 protects the brain from ischemic injury Prostaglandin E2 inhibits neutrophil extracellular trap formation through production of cyclic AMP.Modulation of dendritic cell function by PGE2 and DHA: a framework for understanding the role of dendritic cells in neuroinflammation.Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke.Role of phospholipase A2s and lipid mediators in secondary damage after spinal cord injury.Characterization of microsomal prostaglandin E synthase 1 inhibitors.Inhibitors of microsomal prostaglandin E2 synthase-1 enzyme as emerging anti-inflammatory candidates.Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.Identification of furo[3', 2':3,4]naphtho[1,2-d]imidazole derivatives as orally active and selective inhibitors of microsomal prostaglandin E(2) synthase-1 (mPGES-1).Prostaglandins antagonistically control Bax activation during apoptosis Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesis Microsomal prostaglandin E synthase-1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease-like pathology in a mouse model.Prostaglandin terminal synthases as novel therapeutic targets.Characteristics of cerebral ischemia in major rat stroke models of middle cerebral artery ligation through craniectomy.Hypoxia-independent mechanisms of HIF-1α expression in astrocytes after ischemic preconditioning.Role of the blood-cerebrospinal fluid barrier transporter as a cerebral clearance system for prostaglandin E₂ produced in the brain.Selective inhibitors of human mPGES-1 from structure-based computational screening.Minocycline reduces prostaglandin E synthase expression and 8-isoprostane formation in LPS-activated primary rat microglia.Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs.

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P2860

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

http://www.wikidata.org/entity/Q34830891

description

2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

@ast

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

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Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

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type

label

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

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Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

@en

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

@nl

prefLabel

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

@ast

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

@en

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury.

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Azusa Ota

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Satoshi Uematsu

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Tetsuya Fukada

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Yasuharu Sasaki

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Yuri Ikeda-Matsuo

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P2860

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

Pathobiology of ischaemic stroke: an integrated view

Prostaglandin E synthase

Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2

Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1

Inflammatory mediators and stroke: new opportunities for novel therapeutics.

Thrombolysis for acute stroke.

Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice.

Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia.

Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke.

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reperfusion injury

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