Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression - Wikidata - awgldk - TriplyDB

Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression

Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression

http://www.wikidata.org/entity/Q34831211

about

Small-molecule screening and profiling by using automated microscopy.Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy.Therapeutic blockade of T-cell antigen receptor signal transduction and costimulation in autoimmune disease T cell IFN-γ suppression following alcohol and burn injury is independent of miRNA155.High-content siRNA screening for target identification and validation.MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells Noninvasive diagnosis of acute cellular rejection in liver transplant recipients: a proteomic signature validated by enzyme-linked immunosorbent assay NFAT as cancer target: mission possible?Cannabinoid receptor 2 suppresses leukocyte inflammatory migration by modulating the JNK/c-Jun/Alox5 pathway T-cell-targeted signaling inhibitors.TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.Systematizing serendipity for cardiovascular drug discovery.Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling.Inhibiting the calcineurin-NFAT (nuclear factor of activated T cells) signaling pathway with a regulator of calcineurin-derived peptide without affecting general calcineurin phosphatase activity.miR-9 enhances the transactivation of nuclear factor of activated T cells by targeting KPNB1 and DYRK1B.Inhibition of the calcineurin-NFAT interaction by small organic molecules reflects binding at an allosteric site.Serine/Threonine phosphatases: classification, roles and pharmacological regulation.New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B

P2860

Q31132679-877545F3-1895-48D4-A5B5-1B4DB4C20BC9 Q33753720-4D1577A3-676D-4B26-829F-E6180E84534A Q33785953-D759E640-A54F-4613-81E8-7B483ACB915C Q34051033-03E73AAA-66B5-4C56-A7C0-2B5A130A9B67 Q34619274-4E8A228B-B063-43FB-B055-03822C1B625D Q34818972-8F027CF1-A222-48D0-9B96-8ED781BBD7C3 Q35802158-764D519B-A0E0-4756-BE31-C20C914890C0 Q36455193-69181E1F-E169-458C-9710-196E2378F460 Q36832642-853C34B2-F3F9-4DD0-8FC2-9DE103773A1F Q37094686-DBE05339-AC10-4E00-8C21-30048D60FFF0 Q37139035-EB1C5C64-F94E-4A91-AEAB-7560967E6355 Q37557135-1F71AE3B-4F5C-45C9-8618-4A1CAB3EE70C Q37622487-430F9EF9-7447-4F0A-8A8E-93CB09362FAE Q39076684-275EAA9E-E3E9-49BC-9054-CAAB2EDA8BE7 Q39887982-51856952-4A65-4862-B4C6-16E2D6819EEC Q41390605-79ACAF49-470A-4468-BBE4-FC9F9C426A40 Q46691166-3905EA1A-B3DC-443B-831A-682DAC380620 Q52977222-2667D10C-9E6D-4252-8F7D-CEFC82147725 Q57201013-5D6BA789-0103-4642-83F4-A7690E3FF5FA

P2860

Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression

http://www.wikidata.org/entity/Q34831211

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Chemical genetics to identify ...... ilization in immunosuppression

@ast

Chemical genetics to identify ...... ilization in immunosuppression

@en

Chemical genetics to identify ...... ilization in immunosuppression

@nl

type

label

Chemical genetics to identify ...... ilization in immunosuppression

@ast

Chemical genetics to identify ...... ilization in immunosuppression

@en

Chemical genetics to identify ...... ilization in immunosuppression

@nl

prefLabel

Chemical genetics to identify ...... ilization in immunosuppression

@ast

Chemical genetics to identify ...... ilization in immunosuppression

@en

Chemical genetics to identify ...... ilization in immunosuppression

@nl

P1433

Q34831211-DAEF7566-64E8-41CC-8447-215B95BC6C09

P1476

Q34831211-FD99A754-BE71-4C1B-B583-9C7CF92D5737

P2093

Q34831211-749FB953-FDE0-4DEB-B7AF-D96BA7D61CDC

Q34831211-9085B856-D28E-45ED-B149-A01697518CBF

Q34831211-ABE0C3BE-F57E-42B2-BA6D-14BEAC44C322

Q34831211-B7455ADA-6D50-46B6-A8B6-DACDCFB1C052

Q34831211-CC5F9338-EBA9-45C9-8FCD-5C96C64F69B8

Q34831211-D8A21E1F-0744-4093-A2DF-6E4203ADB426

Q34831211-F45B186D-9275-49A9-BDFB-210B58A8ABDA

P2860

Q34831211-11E942D9-1398-4225-A733-CFD28B767241

Q34831211-12506A57-D000-4F97-80C6-725DF2763121

Q34831211-1450F0DC-AEB0-4D85-9ABB-3627C9A9F3A5

Q34831211-19120E8E-38CC-49FD-B19B-5F2A08235A85

Q34831211-1DF38EF1-69E4-4864-ACF6-BDFBE55D17AD

Q34831211-273CFE95-877A-4C06-BEED-4BDE89F69EA6

Q34831211-37D2D100-C176-4937-883C-E0AD5DD625BF

Q34831211-3EEAA0B1-009D-4B57-8C99-4A6EA88369CA

Q34831211-4020540A-FDD4-4E9A-9B3F-541C15CE5C07

Q34831211-4E16B4EA-401E-4A01-ADAD-16BE398F8671

P304

Q34831211-EDA71ED0-D00A-462E-9CAF-A21402F59DBA

P31

Q34831211-C05F1728-20C3-45C3-832D-C4F3CB9D0772

P356

Q34831211-868BAD35-EED2-4178-8ABB-B26CD3D5A879

P407

Q34831211-87257B52-FD92-46FC-A8C1-EE83C246D914

P433

Q34831211-0077EFFF-1C86-482F-A824-4BA9026451C5

P478

Q34831211-8B527D77-6B7C-4A64-AD84-B9696EA4CE19

P577

Q34831211-CB0122F3-193B-43A9-9BEE-9A7F21053D2F

P5875

Q34831211-D12C2927-D5D0-41ED-9E0A-FCD6688E7B48

P698

Q34831211-70F56283-8175-45B7-A612-7BCD1AB141A6

P921

Q34831211-7E69AECD-5DF5-4E13-9069-6CE14A08F53D

P932

Q34831211-F0DF5F9E-3B45-48C7-8DC3-25A7111288C7

P356

PNAS.0402803101

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Chemical genetics to identify ...... ilization in immunosuppression

@en

P2093

Brian DeDecker

http://www.w3.org/2001/XMLSchema#string

David Golan

http://www.w3.org/2001/XMLSchema#string

Frank McKeon

http://www.w3.org/2001/XMLSchema#string

Natarajan Venkatesh

http://www.w3.org/2001/XMLSchema#string

Patrick Yacono

http://www.w3.org/2001/XMLSchema#string

Timothy Mitchison

http://www.w3.org/2001/XMLSchema#string

Yan Feng

http://www.w3.org/2001/XMLSchema#string

P2860

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

NFAT signaling: choreographing the social lives of cells

Transcription factors of the NFAT family: regulation and function

Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

The transcription factor NFAT4 is involved in the generation and survival of T cells

Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp)

Transcriptional regulation by calcium, calcineurin, and NFAT

Nuclear transport and transcription.

Nucleocytoplasmic shuttling and the control of NF-AT signaling.

P304

8969-8974

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0402803101

http://www.w3.org/2001/XMLSchema#string

P407

P433

24

http://www.w3.org/2001/XMLSchema#string

P478

101

http://www.w3.org/2001/XMLSchema#string

P577

2004-06-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8521781

http://www.w3.org/2001/XMLSchema#string

P698

15184684

http://www.w3.org/2001/XMLSchema#string

P921

immunosuppression

P932

428456

http://www.w3.org/2001/XMLSchema#string