Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor.
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Voltage-Controlled Enzymes: The New JanusBifronsVoltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domainsIndependent movement of the voltage sensors in KV2.1/KV6.4 heterotetramersMoving gating charges through the gating pore in a Kv channel voltage sensor.Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.Evidence for functional diversity between the voltage-gated proton channel Hv1 and its closest related protein HVRP1.Structural interactions between lipids, water and S1-S4 voltage-sensing domainsThe free energy barrier for arginine gating charge translation is altered by mutations in the voltage sensor domain.Capturing distinct KCNQ2 channel resting states by metal ion bridges in the voltage-sensor domain.Electric fingerprint of voltage sensor domains.Estimating the voltage-dependent free energy change of ion channels using the median voltage for activationGating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain.Microscopic origin of gating current fluctuations in a potassium channel voltage sensorCoupling between the voltage-sensing and pore domains in a voltage-gated potassium channel.Intermediate state trapping of a voltage sensorThe conserved phenylalanine in the K+ channel voltage-sensor domain creates a barrier with unidirectional effects.Opening the shaker K+ channel with hanatoxin.Allosteric substrate switching in a voltage-sensing lipid phosphataseThe α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentialsMutations in the S6 gate isolate a late step in the activation pathway and reduce 4-AP sensitivity in shaker K(v) channel.Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domainDivining the design principles of voltage sensors.Evolutionary imprint of activation: the design principles of VSDs.Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains.Voltage-dependent gating of HERG potassium channels.Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels.Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.Tetraphenylporphyrin derivative specifically blocks members of the voltage-gated potassium channel subfamily Kv1.Transfer of Kv3.1 voltage sensor features to the isolated Ci-VSP voltage-sensing domain.Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels.Voltage-sensor transitions of the inward-rectifying K+ channel KAT1 indicate a latching mechanism biased by hydration within the voltage sensor.Tuning the voltage-sensor motion with a single residue.Voltage dependence of Hodgkin-Huxley rate functions for a multistage K^{+} channel voltage sensor within a membrane.Commentary: A channelopathy mutation in the voltage-sensor discloses contributions of a conserved phenylalanine to gating properties of Kv1.1 channels and ataxia.
P2860
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P2860
Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor.
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2011 nî lūn-bûn
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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2011 թվականի ապրիլին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
@zh-hk
2011年論文
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2011年論文
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2011年论文
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name
Control of a final gating char ...... f a K+ channel voltage sensor.
@ast
Control of a final gating char ...... f a K+ channel voltage sensor.
@en
Control of a final gating char ...... f a K+ channel voltage sensor.
@nl
type
label
Control of a final gating char ...... f a K+ channel voltage sensor.
@ast
Control of a final gating char ...... f a K+ channel voltage sensor.
@en
Control of a final gating char ...... f a K+ channel voltage sensor.
@nl
prefLabel
Control of a final gating char ...... f a K+ channel voltage sensor.
@ast
Control of a final gating char ...... f a K+ channel voltage sensor.
@en
Control of a final gating char ...... f a K+ channel voltage sensor.
@nl
P2860
P356
P1476
Control of a final gating char ...... f a K+ channel voltage sensor.
@en
P2093
Francisco Bezanilla
Jérôme J Lacroix
P2860
P304
P356
10.1073/PNAS.1103397108
P407
P577
2011-04-04T00:00:00Z